UNC5A

Unc-5 homolog A (C. elegans), also known as UNC5A, is a human gene.cite web | title = Entrez Gene: UNC5A unc-5 homolog A (C. elegans)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=90249| accessdate = ]

PBB_Summary
section_title =
summary_text = UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610). [supplied by OMIM] cite web | title = Entrez Gene: UNC5A unc-5 homolog A (C. elegans)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=90249| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Arakawa H |title=Netrin-1 and its receptors in tumorigenesis. |journal=Nat. Rev. Cancer |volume=4 |issue= 12 |pages= 978–87 |year= 2005 |pmid= 15573119 |doi= 10.1038/nrc1504
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Nagase T, Kikuno R, Ohara O |title=Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. |journal=DNA Res. |volume=8 |issue= 6 |pages= 319–27 |year= 2002 |pmid= 11853319 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Williams ME, Strickland P, Watanabe K, Hinck L |title=UNC5H1 induces apoptosis via its juxtamembrane region through an interaction with NRAGE. |journal=J. Biol. Chem. |volume=278 |issue= 19 |pages= 17483–90 |year= 2003 |pmid= 12598531 |doi= 10.1074/jbc.M300415200
*cite journal | author=Tanikawa C, Matsuda K, Fukuda S, "et al." |title=p53RDL1 regulates p53-dependent apoptosis. |journal=Nat. Cell Biol. |volume=5 |issue= 3 |pages= 216–23 |year= 2003 |pmid= 12598906 |doi= 10.1038/ncb943
*cite journal | author=Thiebault K, Mazelin L, Pays L, "et al." |title=The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 7 |pages= 4173–8 |year= 2003 |pmid= 12655055 |doi= 10.1073/pnas.0738063100
*cite journal | author=Geisbrecht BV, Dowd KA, Barfield RW, "et al." |title=Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin. |journal=J. Biol. Chem. |volume=278 |issue= 35 |pages= 32561–8 |year= 2003 |pmid= 12810718 |doi= 10.1074/jbc.M302943200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Llambi F, Lourenço FC, Gozuacik D, "et al." |title=The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase. |journal=EMBO J. |volume=24 |issue= 6 |pages= 1192–201 |year= 2005 |pmid= 15729359 |doi= 10.1038/sj.emboj.7600584

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