C6orf25

Chromosome 6 open reading frame 25, also known as C6orf25, is a human gene.

PBB_Summary
section_title =
summary_text = This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.cite web | title = Entrez Gene: C6orf25 chromosome 6 open reading frame 25| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80739| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Ribas G, Neville M, Wixon JL, "et al." |title=Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region. |journal=J. Immunol. |volume=163 |issue= 1 |pages= 278–87 |year= 1999 |pmid= 10384126 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000
*cite journal | author=de Vet EC, Aguado B, Campbell RD |title=G6b, a novel immunoglobulin superfamily member encoded in the human major histocompatibility complex, interacts with SHP-1 and SHP-2. |journal=J. Biol. Chem. |volume=276 |issue= 45 |pages= 42070–6 |year= 2001 |pmid= 11544253 |doi= 10.1074/jbc.M103214200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Xie T, Rowen L, Aguado B, "et al." |title=Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. |journal=Genome Res. |volume=13 |issue= 12 |pages= 2621–36 |year= 2004 |pmid= 14656967 |doi= 10.1101/gr.1736803
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=de Vet EC, Newland SA, Lyons PA, "et al." |title=The cell surface receptor G6b, a member of the immunoglobulin superfamily, binds heparin. |journal=FEBS Lett. |volume=579 |issue= 11 |pages= 2355–8 |year= 2005 |pmid= 15848171 |doi= 10.1016/j.febslet.2005.03.032
*cite journal | author=Newland SA, Macaulay IC, Floto AR, "et al." |title=The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro. |journal=Blood |volume=109 |issue= 11 |pages= 4806–9 |year= 2007 |pmid= 17311996 |doi= 10.1182/blood-2006-09-047449
*cite journal | author=Li J, Cadeiras M, Prinz von Bayern M, "et al." |title=G6b-B cell surface inhibitory receptor expression is highly restricted to CD4+ T-cells and induced by interleukin-4-activated STAT6 pathway. |journal=Hum. Immunol. |volume=68 |issue= 8 |pages= 708–14 |year= 2007 |pmid= 17678728 |doi= 10.1016/j.humimm.2007.04.008

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