RNF34

Ring finger protein 34, also known as RNF34, is a human gene.cite web | title = Entrez Gene: RNF34 ring finger protein 34| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80196| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.cite web | title = Entrez Gene: RNF34 ring finger protein 34| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80196| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Sasaki S, Nakamura T, Arakawa H, "et al." |title=Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer. |journal=Oncogene |volume=21 |issue= 32 |pages= 5024–30 |year= 2002 |pmid= 12118383 |doi= 10.1038/sj.onc.1205627
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=McDonald ER, El-Deiry WS |title=Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 16 |pages= 6170–5 |year= 2004 |pmid= 15069192 |doi= 10.1073/pnas.0307459101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Sasaki S, Watanabe T, Konishi T, "et al." |title=Effects of expression of hRFI on adenoma formation and tumor progression in colorectal adenoma-carcinoma sequence. |journal=J. Exp. Clin. Cancer Res. |volume=23 |issue= 3 |pages= 507–12 |year= 2005 |pmid= 15595643 |doi=
*cite journal | author=Konishi T, Sasaki S, Watanabe T, "et al." |title=Overexpression of hRFI (human ring finger homologous to inhibitor of apoptosis protein type) inhibits death receptor-mediated apoptosis in colorectal cancer cells. |journal=Mol. Cancer Ther. |volume=4 |issue= 5 |pages= 743–50 |year= 2005 |pmid= 15897238 |doi= 10.1158/1535-7163.MCT-05-0020
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

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