TNNC2

Troponin C type 2 (fast), also known as TNNC2, is a human gene.cite web | title = Entrez Gene: TNNC2 troponin C type 2 (fast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7125| accessdate = ]

PBB_Summary
section_title =
summary_text = Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.cite web | title = Entrez Gene: TNNC2 troponin C type 2 (fast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7125| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Romero-Herrera AE, Castillo O, Lehmann H |title=Human skeletal muscle proteins. The primary structure of troponin C. |journal=J. Mol. Evol. |volume=8 |issue= 3 |pages= 251–70 |year= 1977 |pmid= 978749 |doi=
*cite journal | author=Tomasselli AG, Hui JO, Adams L, "et al." |title=Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus. |journal=J. Biol. Chem. |volume=266 |issue= 22 |pages= 14548–53 |year= 1991 |pmid= 1907279 |doi=
*cite journal | author=Gahlmann R, Kedes L |title=Cloning, structural analysis, and expression of the human fast twitch skeletal muscle troponin C gene. |journal=J. Biol. Chem. |volume=265 |issue= 21 |pages= 12520–8 |year= 1990 |pmid= 2373703 |doi=
*cite journal | author=Gahlmann R, Wade R, Gunning P, Kedes L |title=Differential expression of slow and fast skeletal muscle troponin C. Slow skeletal muscle troponin C is expressed in human fibroblasts. |journal=J. Mol. Biol. |volume=201 |issue= 2 |pages= 379–91 |year= 1988 |pmid= 3166492 |doi=
*cite journal | author=Prentice H, Kloner RA, Prigozy T, "et al." |title=Tissue restricted gene expression assayed by direct DNA injection into cardiac and skeletal muscle. |journal=J. Mol. Cell. Cardiol. |volume=26 |issue= 10 |pages= 1393–401 |year= 1995 |pmid= 7869399 |doi= 10.1006/jmcc.1994.1157
*cite journal | author=Tiso N, Rampoldi L, Pallavicini A, "et al." |title=Fine mapping of five human skeletal muscle genes: alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast. |journal=Biochem. Biophys. Res. Commun. |volume=230 |issue= 2 |pages= 347–50 |year= 1997 |pmid= 9016781 |doi= 10.1006/bbrc.1996.5958
*cite journal | author=Townsend PJ, Yacoub MH, Barton PJ |title=Assignment of the human fast skeletal muscle troponin C gene (TNNC2) between D20S721 and GCT10F11 on chromosome 20 by somatic cell hybrid analysis. |journal=Ann. Hum. Genet. |volume=61 |issue= Pt 5 |pages= 457–9 |year= 1998 |pmid= 9459007 |doi= 10.1046/j.1469-1809.1997.6150457.x
*cite journal | author=Vassylyev DG, Takeda S, Wakatsuki S, "et al." |title=Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 9 |pages= 4847–52 |year= 1998 |pmid= 9560191 |doi=
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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