PTTG1IP

Pituitary tumor-transforming 1 interacting protein, also known as PTTG1IP, is a human gene.cite web | title = Entrez Gene: PTTG1IP pituitary tumor-transforming 1 interacting protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=754| accessdate = ]

PBB_Summary
section_title =
summary_text = The encoded protein, which directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.cite web | title = Entrez Gene: PTTG1IP pituitary tumor-transforming 1 interacting protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=754| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yaspo ML, Aaltonen J, Horelli-Kuitunen N, "et al." |title=Cloning of a novel human putative type Ia integral membrane protein mapping to 21q22.3. |journal=Genomics |volume=49 |issue= 1 |pages= 133–6 |year= 1998 |pmid= 9570958 |doi= 10.1006/geno.1998.5217
*cite journal | author=Chien W, Pei L |title=A novel binding factor facilitates nuclear translocation and transcriptional activation function of the pituitary tumor-transforming gene product. |journal=J. Biol. Chem. |volume=275 |issue= 25 |pages= 19422–7 |year= 2000 |pmid= 10781616 |doi= 10.1074/jbc.M910105199
*cite journal | author=Hattori M, Fujiyama A, Taylor TD, "et al." |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Boelaert K, Tannahill LA, Bulmer JN, "et al." |title=A potential role for PTTG/securin in the developing human fetal brain. |journal=FASEB J. |volume=17 |issue= 12 |pages= 1631–9 |year= 2003 |pmid= 12958169 |doi= 10.1096/fj.02-0948com
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Tfelt-Hansen J, Yano S, Bandyopadhyay S, "et al." |title=Expression of pituitary tumor transforming gene (PTTG) and its binding protein in human astrocytes and astrocytoma cells: function and regulation of PTTG in U87 astrocytoma cells. |journal=Endocrinology |volume=145 |issue= 9 |pages= 4222–31 |year= 2004 |pmid= 15178645 |doi= 10.1210/en.2003-1661
*cite journal | author=Stock M, Schäfer H, Fliegauf M, Otto F |title=Identification of novel genes of the bone-specific transcription factor Runx2. |journal=J. Bone Miner. Res. |volume=19 |issue= 6 |pages= 959–72 |year= 2005 |pmid= 15190888 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Boelaert K, Smith VE, Stratford AL, "et al." |title=PTTG and PBF repress the human sodium iodide symporter. |journal=Oncogene |volume=26 |issue= 30 |pages= 4344–56 |year= 2007 |pmid= 17297475 |doi= 10.1038/sj.onc.1210221

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