- RBMS1
RNA binding motif, single stranded interacting protein 1, also known as RBMS1, is a human
gene .cite web | title = Entrez Gene: RBMS1 RNA binding motif, single stranded interacting protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5937| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Multiple transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. Several of these were isolated by virtue of their binding to either strand of an upstream element of c-myc (MSSPs), or by phenotypic complementation of cdc2 and cdc13 mutants of yeast (scr2), or as a potential human repressor of HIV-1 and ILR-2 alpha promoter transcription (YC1). A pseudogene for this locus is found on chromosome 12.cite web | title = Entrez Gene: RBMS1 RNA binding motif, single stranded interacting protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5937| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Takai T, Nishita Y, Iguchi-Ariga SM, Ariga H |title=Molecular cloning of MSSP-2, a c-myc gene single-strand binding protein: characterization of binding specificity and DNA replication activity. |journal=Nucleic Acids Res. |volume=22 |issue= 25 |pages= 5576–81 |year= 1995 |pmid= 7838710 |doi=
*cite journal | author=Kanaoka Y, Nojima H |title=SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins. |journal=Nucleic Acids Res. |volume=22 |issue= 13 |pages= 2687–93 |year= 1994 |pmid= 8041632 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Negishi Y, Nishita Y, Saëgusa Y, "et al." |title=Identification and cDNA cloning of single-stranded DNA binding proteins that interact with the region upstream of the human c-myc gene. |journal=Oncogene |volume=9 |issue= 4 |pages= 1133–43 |year= 1994 |pmid= 8134115 |doi=
*cite journal | author=Haigermoser C, Fujimoto M, Iguchi-Ariga SM, Ariga H |title=Cloning and characterization of the genomic DNA of the human MSSP genes. |journal=Nucleic Acids Res. |volume=24 |issue= 19 |pages= 3846–57 |year= 1996 |pmid= 8871567 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Niki T, Galli I, Ariga H, Iguchi-Ariga SM |title=MSSP, a protein binding to an origin of replication in the c-myc gene, interacts with a catalytic subunit of DNA polymerase alpha and stimulates its polymerase activity. |journal=FEBS Lett. |volume=475 |issue= 3 |pages= 209–12 |year= 2000 |pmid= 10869558 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504PBB_Controls
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