PTPRCAP

Protein tyrosine phosphatase, receptor type, C-associated protein, also known as PTPRCAP, is a human gene.cite web | title = Entrez Gene: PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5790| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene was identified as a transmembrane phosphoprotein specifically associated with tyrosine phosphatase PTPRC/CD45, a key regulator of T- and B-lymphocyte activation. The interaction with PTPRC may be required for the stable expression of this protein.cite web | title = Entrez Gene: PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5790| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Schraven B, Schoenhaut D, Bruyns E, "et al." |title=LPAP, a novel 32-kDa phosphoprotein that interacts with CD45 in human lymphocytes. |journal=J. Biol. Chem. |volume=269 |issue= 46 |pages= 29102–11 |year= 1994 |pmid= 7961877 |doi=
*cite journal | author=Bruyns E, Hendricks-Taylor LR, Meuer S, "et al." |title=Identification of the sites of interaction between lymphocyte phosphatase-associated phosphoprotein (LPAP) and CD45. |journal=J. Biol. Chem. |volume=270 |issue= 52 |pages= 31372–6 |year= 1996 |pmid= 8537410 |doi=
*cite journal | author=Bruyns E, Mincheva A, Bruyns RM, "et al." |title=Sequence, genomic organization, and chromosomal localization of the human LPAP (PTPRCAP) and mouse CD45-AP/LSM-1 genes. |journal=Genomics |volume=38 |issue= 1 |pages= 79–83 |year= 1997 |pmid= 8954783 |doi= 10.1006/geno.1996.0595
*cite journal | author=Kung C, Okumura M, Seavitt JR, "et al." |title=CD45-associated protein is not essential for the regulation of antigen receptor-mediated signal transduction. |journal=Eur. J. Immunol. |volume=29 |issue= 12 |pages= 3951–5 |year= 2000 |pmid= 10602003 |doi=
*cite journal | author=Woods ML, Kivens WJ, Adelsman MA, "et al." |title=A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor. |journal=EMBO J. |volume=20 |issue= 6 |pages= 1232–44 |year= 2001 |pmid= 11250890 |doi= 10.1093/emboj/20.6.1232
*cite journal | author=Kirchgessner H, Dietrich J, Scherer J, "et al." |title=The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. |journal=J. Exp. Med. |volume=193 |issue= 11 |pages= 1269–84 |year= 2001 |pmid= 11390434 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Vogel A, Strassburg CP, Manns MP |title=77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic link. |journal=Genes Immun. |volume=4 |issue= 1 |pages= 79–81 |year= 2003 |pmid= 12595907 |doi= 10.1038/sj.gene.6363918
*cite journal | author=Cocco E, Murru MR, Melis C, "et al." |title=PTPRC (CD45) C77G mutation does not contribute to multiple sclerosis susceptibility in Sardinian patients. |journal=J. Neurol. |volume=251 |issue= 9 |pages= 1085–8 |year= 2004 |pmid= 15372250 |doi= 10.1007/s00415-004-0485-1
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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