Immune Epitope Database and Analysis Resource

Immune Epitope Database and Analysis Resource

The Immune Epitope Database and Analysis Resource (IEDB) is a project hosted by scientists at the La Jolla Institute for Allergy and Immunology (LIAI), with support from the [http://www.niaid.nih.gov/default.htm National Institute of Allergy and Infectious Diseases] (NIAID), a part of the [http://www.nih.gov/default.htm National Institutes of Health] (NIH), and [http://www.hhs.gov/ Department of Health and Human Services] (HHS). While not strictly limited, the current focus is presenting information that facilitates the dissemination of immune epitope information, the generation of new research tools, diagnostic techniques, vaccines and therapeutics for emerging and re-emerging diseases.

The IEDB contains data related to antibody and T cell epitopes for humans, non-human primates, rodents, and other animal species. Curation of data relating to [http://www3.niaid.nih.gov/research/topics/emerging/list.htm NIAID Category A, B, and C priority pathogens] (including Influenza) and [http://www3.niaid.nih.gov/research/topics/emerging/default.htm NIAID Emerging and Re-emerging infectious diseases] is complete through June 2007. Curation of Malaria, Hepatitis B, "Clostridium tetani", "Leishmania", and "Candida albicans" is current through June 2007. Present efforts include herpes viruses and allergen epitopes. Curation of autoimmune epitopes will start in second quarter 2008.

The database also contains MHC binding data from a variety of different antigenic sources and immune epitope data from the FIMM (Brusic), HLA Ligand (Hildebrand), TopBank (Sette), and MHC binding (Buus) databases. These databases and their investigators are hereby acknowledged as major contributors to the IEDB.

For more information about our curation procedures please refer to the IEDB [http://tools.immuneepitope.org/wiki/index.php/Curation_Manual Curation Manual] .

External links

* [http://www.immuneEPITOPE.org/ Immune Epitope Database and Analysis Resource]
*La Jolla Institute for Allergy and Immunology


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