TRMU

TRNA 5-methylaminomethyl-2-thiouridylate methyltransferase, also known as TRMU, is a human gene.cite web | title = Entrez Gene: TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55687| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.cite web | title = Entrez Gene: TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55687| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Dunham I, Shimizu N, Roe BA, "et al." |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Yan Q, Guan MX |title=Identification and characterization of mouse TRMU gene encoding the mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase. |journal=Biochim. Biophys. Acta |volume=1676 |issue= 2 |pages= 119–26 |year= 2004 |pmid= 14746906 |doi=
*cite journal | author=Collins JE, Wright CL, Edwards CA, "et al." |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84
*cite journal | author=Umeda N, Suzuki T, Yukawa M, "et al." |title=Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. |journal=J. Biol. Chem. |volume=280 |issue= 2 |pages= 1613–24 |year= 2005 |pmid= 15509579 |doi= 10.1074/jbc.M409306200
*cite journal | author=Yan Q, Li X, Faye G, Guan MX |title=Mutations in MTO2 related to tRNA modification impair mitochondrial gene expression and protein synthesis in the presence of a paromomycin resistance mutation in mitochondrial 15 S rRNA. |journal=J. Biol. Chem. |volume=280 |issue= 32 |pages= 29151–7 |year= 2005 |pmid= 15944150 |doi= 10.1074/jbc.M504247200
*cite journal | author=Oh JH, Yang JO, Hahn Y, "et al." |title=Transcriptome analysis of human gastric cancer. |journal=Mamm. Genome |volume=16 |issue= 12 |pages= 942–54 |year= 2006 |pmid= 16341674 |doi= 10.1007/s00335-005-0075-2
*cite journal | author=Yan Q, Bykhovskaya Y, Li R, "et al." |title=Human TRMU encoding the mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase is a putative nuclear modifier gene for the phenotypic expression of the deafness-associated 12S rRNA mutations. |journal=Biochem. Biophys. Res. Commun. |volume=342 |issue= 4 |pages= 1130–6 |year= 2006 |pmid= 16513084 |doi= 10.1016/j.bbrc.2006.02.078
*cite journal | author=Guan MX, Yan Q, Li X, "et al." |title=Mutation in TRMU related to transfer RNA modification modulates the phenotypic expression of the deafness-associated mitochondrial 12S ribosomal RNA mutations. |journal=Am. J. Hum. Genet. |volume=79 |issue= 2 |pages= 291–302 |year= 2006 |pmid= 16826519 |doi= 10.1086/506389

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