PNPO

Pyridoxamine 5'-phosphate oxidase, also known as PNPO, is a human gene.cite web | title = Entrez Gene: PNPO pyridoxamine 5'-phosphate oxidase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55163| accessdate = ]

PBB_Summary
section_title =
summary_text = Vitamin B6, or pyridoxal 5-prime-phosphate (PLP), is critical for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. The rate-limiting enzyme in vitamin B6 synthesis is pyridoxine-5-prime-phosphate (PNP) oxidase (PNPO; EC 1.4.3.5). [supplied by OMIM] cite web | title = Entrez Gene: PNPO pyridoxamine 5'-phosphate oxidase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55163| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Ngo EO, LePage GR, Thanassi JW, "et al." |title=Absence of pyridoxine-5'-phosphate oxidase (PNPO) activity in neoplastic cells: isolation, characterization, and expression of PNPO cDNA. |journal=Biochemistry |volume=37 |issue= 21 |pages= 7741–8 |year= 1998 |pmid= 9601034 |doi= 10.1021/bi972983r
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Musayev FN, Di Salvo ML, Ko TP, "et al." |title=Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase. |journal=Protein Sci. |volume=12 |issue= 7 |pages= 1455–63 |year= 2004 |pmid= 12824491 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Kang JH, Hong ML, Kim DW, "et al." |title=Genomic organization, tissue distribution and deletion mutation of human pyridoxine 5'-phosphate oxidase. |journal=Eur. J. Biochem. |volume=271 |issue= 12 |pages= 2452–61 |year= 2004 |pmid= 15182361 |doi= 10.1111/j.1432-1033.2004.04175.x
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Mills PB, Surtees RA, Champion MP, "et al." |title=Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase. |journal=Hum. Mol. Genet. |volume=14 |issue= 8 |pages= 1077–86 |year= 2005 |pmid= 15772097 |doi= 10.1093/hmg/ddi120
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

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