ENPP3

Ectonucleotide pyrophosphatase/phosphodiesterase 3, also known as ENPP3, is a human gene.cite web | title = Entrez Gene: ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5169| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells.cite web | title = Entrez Gene: ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5169| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Bühring HJ, Streble A, Valent P |title=The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis. |journal=Int. Arch. Allergy Immunol. |volume=133 |issue= 4 |pages= 317–29 |year= 2004 |pmid= 15031605 |doi= 10.1159/000077351
*cite journal | author=Jin-Hua P, Goding JW, Nakamura H, Sano K |title=Molecular cloning and chromosomal localization of PD-Ibeta (PDNP3), a new member of the human phosphodiesterase I genes. |journal=Genomics |volume=45 |issue= 2 |pages= 412–5 |year= 1998 |pmid= 9344668 |doi= 10.1006/geno.1997.4949
*cite journal | author=Andoh K, Piao JH, Terashima K, "et al." |title=Genomic structure and promoter analysis of the ecto-phosphodiesterase I gene (PDNP3) expressed in glial cells. |journal=Biochim. Biophys. Acta |volume=1446 |issue= 3 |pages= 213–24 |year= 1999 |pmid= 10524196 |doi=
*cite journal | author=Bühring HJ, Seiffert M, Giesert C, "et al." |title=The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3. |journal=Blood |volume=97 |issue= 10 |pages= 3303–5 |year= 2001 |pmid= 11342463 |doi=
*cite journal | author=Yano Y, Hayashi Y, Sano K, "et al." |title=Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-3 (E-NPP3/CD203c/PD-I beta/B10/gp130RB13-6) in human colon carcinoma. |journal=Int. J. Mol. Med. |volume=12 |issue= 5 |pages= 763–6 |year= 2004 |pmid= 14533006 |doi=
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Yano Y, Hayashi Y, Sano K, "et al." |title=Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-1 (E-NPP1/PC-1) and -3 (E-NPP3/CD203c/PD-Ibeta/B10/gp130(RB13-6)) in inflammatory and neoplastic bile duct diseases. |journal=Cancer Lett. |volume=207 |issue= 2 |pages= 139–47 |year= 2004 |pmid= 15072822 |doi= 10.1016/j.canlet.2003.11.002
*cite journal | author=Elbatarny HS, Maurice DH |title=Leptin-mediated activation of human platelets: involvement of a leptin receptor and phosphodiesterase 3A-containing cellular signaling complex. |journal=Am. J. Physiol. Endocrinol. Metab. |volume=289 |issue= 4 |pages= E695–702 |year= 2005 |pmid= 15886225 |doi= 10.1152/ajpendo.00125.2005
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Ocmant A, Peignois Y, Mulier S, "et al." |title=Flow cytometry for basophil activation markers: the measurement of CD203c up-regulation is as reliable as CD63 expression in the diagnosis of cat allergy. |journal=J. Immunol. Methods |volume=320 |issue= 1-2 |pages= 40–8 |year= 2007 |pmid= 17275019 |doi= 10.1016/j.jim.2006.12.002

PBB_Controls
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update_summary = yes
update_citations = yes