CKLF (gene)

Chemokine-like factor, also known as CKLF, is a human gene.cite web | title = Entrez Gene: CKLF chemokine-like factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51192| accessdate = ]

PBB_Summary
section_title =
summary_text = The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified.cite web | title = Entrez Gene: CKLF chemokine-like factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51192| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Zhang QH, Ye M, Wu XY, "et al." |title=Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. |journal=Genome Res. |volume=10 |issue= 10 |pages= 1546–60 |year= 2001 |pmid= 11042152 |doi=
*cite journal | author=Han W, Lou Y, Tang J, "et al." |title=Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity. |journal=Biochem. J. |volume=357 |issue= Pt 1 |pages= 127–35 |year= 2001 |pmid= 11415443 |doi=
*cite journal | author=Boudinot P, Salhi S, Blanco M, Benmansour A |title=Viral haemorrhagic septicaemia virus induces vig-2, a new interferon-responsive gene in rainbow trout. |journal=Fish Shellfish Immunol. |volume=11 |issue= 5 |pages= 383–97 |year= 2002 |pmid= 11478515 |doi= 10.1006/fsim.2000.0326
*cite journal | author=Xia D, Li X, Lou Y, "et al." |title=Overexpression of chemokine-like factor 2 promotes the proliferation and survival of C2C12 skeletal muscle cells. |journal=Biochim. Biophys. Acta |volume=1591 |issue= 1-3 |pages= 163–173 |year= 2002 |pmid= 12183067 |doi=
*cite journal | author=Ke X, Jia L, Jing H, "et al." |title=Effects of novel human chemokine-like factor 1 (CKLF1) on bone marrow hematopoietic stem cell/progenitor cell in vitro. |journal=Zhonghua Xue Ye Xue Za Zhi |volume=23 |issue= 6 |pages= 301–3 |year= 2002 |pmid= 12411060 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Xu M, Han W, Qian M, "et al." |title=Last intron of the chemokine-like factor gene contains a putative promoter for the downstream CKLF super family member 1 gene. |journal=Biochem. Biophys. Res. Commun. |volume=313 |issue= 1 |pages= 135–41 |year= 2004 |pmid= 14672709 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

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