CABYR

CABYR

Calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2), also known as CABYR, is a human gene.cite web | title = Entrez Gene: CABYR calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26256| accessdate = ]

PBB_Summary
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summary_text = To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Transcript variants of this gene encode multiple protein isoforms. An additional transcript and isoform has not been fully characterized.cite web | title = Entrez Gene: CABYR calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26256| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Fouquet JP, Kann ML |title=The cytoskeleton of mammalian spermatozoa. |journal=Biol. Cell |volume=81 |issue= 2 |pages= 89–93 |year= 1995 |pmid= 7849610 |doi=
*cite journal | author=Visconti PE, Westbrook VA, Chertihin O, "et al." |title=Novel signaling pathways involved in sperm acquisition of fertilizing capacity. |journal=J. Reprod. Immunol. |volume=53 |issue= 1-2 |pages= 133–50 |year= 2002 |pmid= 11730911 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Naaby-Hansen S, Mandal A, Wolkowicz MJ, "et al." |title=CABYR, a novel calcium-binding tyrosine phosphorylation-regulated fibrous sheath protein involved in capacitation. |journal=Dev. Biol. |volume=242 |issue= 2 |pages= 236–54 |year= 2002 |pmid= 11820818 |doi= 10.1006/dbio.2001.0527
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ficarro S, Chertihin O, Westbrook VA, "et al." |title=Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation. |journal=J. Biol. Chem. |volume=278 |issue= 13 |pages= 11579–89 |year= 2003 |pmid= 12509440 |doi= 10.1074/jbc.M202325200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hsu HC, Lee YL, Cheng TS, "et al." |title=Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain. |journal=Biochem. Biophys. Res. Commun. |volume=329 |issue= 3 |pages= 1108–17 |year= 2005 |pmid= 15752768 |doi= 10.1016/j.bbrc.2005.02.089
*cite journal | author=Kim YH, Jha KN, Mandal A, "et al." |title=Translation and assembly of CABYR coding region B in fibrous sheath and restriction of calcium binding to coding region A. |journal=Dev. Biol. |volume=286 |issue= 1 |pages= 46–56 |year= 2005 |pmid= 16139264 |doi= 10.1016/j.ydbio.2005.07.005
*cite journal | author=Luo C, Xiao X, Liu D, "et al." |title=CABYR is a novel cancer-testis antigen in lung cancer. |journal=Clin. Cancer Res. |volume=13 |issue= 4 |pages= 1288–97 |year= 2007 |pmid= 17317841 |doi= 10.1158/1078-0432.CCR-06-1742

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