CRYM

Crystallin, mu, also known as CRYM, is a human gene.cite web | title = Entrez Gene: CRYM crystallin, mu| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1428| accessdate = ]

PBB_Summary
section_title =
summary_text = Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Multiple alternatively spliced transcript variants have been found for this gene.cite web | title = Entrez Gene: CRYM crystallin, mu| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1428| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kim RY, Gasser R, Wistow GJ |title=mu-crystallin is a mammalian homologue of Agrobacterium ornithine cyclodeaminase and is expressed in human retina. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 19 |pages= 9292–6 |year= 1992 |pmid= 1384048 |doi=
*cite journal | author=Chen H, Phillips HA, Callen DF, "et al." |title=Localization of the human gene for mu-crystallin to chromosome 16p. |journal=Genomics |volume=14 |issue= 4 |pages= 1115–6 |year= 1993 |pmid= 1478656 |doi=
*cite journal | author=Vié MP, Blanchet P, Samson M, "et al." |title=High affinity thyroid hormone-binding protein in human kidney: kinetic characterization and identification by photoaffinity labeling. |journal=Endocrinology |volume=137 |issue= 11 |pages= 4563–70 |year= 1996 |pmid= 8895318 |doi=
*cite journal | author=Segovia L, Horwitz J, Gasser R, Wistow G |title=Two roles for mu-crystallin: a lens structural protein in diurnal marsupials and a possible enzyme in mammalian retinas. |journal=Mol. Vis. |volume=3 |issue= |pages= 9 |year= 1998 |pmid= 9285773 |doi=
*cite journal | author=Vié MP, Evrard C, Osty J, "et al." |title=Purification, molecular cloning, and functional expression of the human nicodinamide-adenine dinucleotide phosphate-regulated thyroid hormone-binding protein. |journal=Mol. Endocrinol. |volume=11 |issue= 11 |pages= 1728–36 |year= 1998 |pmid= 9328354 |doi=
*cite journal | author=Loftus BJ, Kim UJ, Sneddon VP, "et al." |title=Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. |journal=Genomics |volume=60 |issue= 3 |pages= 295–308 |year= 1999 |pmid= 10493829 |doi= 10.1006/geno.1999.5927
*cite journal | author=Abe S, Katagiri T, Saito-Hisaminato A, "et al." |title=Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues. |journal=Am. J. Hum. Genet. |volume=72 |issue= 1 |pages= 73–82 |year= 2003 |pmid= 12471561 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Reed PW, Corse AM, Porter NC, "et al." |title=Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy. |journal=Exp. Neurol. |volume=205 |issue= 2 |pages= 583–6 |year= 2007 |pmid= 17451686 |doi= 10.1016/j.expneurol.2007.03.009

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