CSE

CSE may refer to:
* Certificate of Secondary Education, a UK examination
* Centre for Science and Environment, an Indian non-governmental organization
* Chalmers School of Entrepreneurship, a Master's Program at Chalmers University of Technology and University of Gothenburg
* Colombo Stock Exchange, a Sri Lankan stock exchange
* Combined spinal and epidural anaesthesia, an anaesthetic technique
* Common subexpression elimination, a compiler optimization technique
* Communications Security Establishment Canada, a Canadian intelligence agency
* Computational Science and Engineering, the science and engineering of computation, usually associated with High Performance Computing
* Computer Science and Engineering, a Bachelor of Engineering degree
* Computer Systems Engineering, a Bachelor of Engineering course
* Copenhagen Stock Exchange, a Danish stock exchange
* Corpus Speculorum Etruscorum, a project to publish all existing Etruscan mirrors
* Council of Science Editors
* Creation Science Evangelism, a Christian apologetics ministry of Kent Hovind
* Crime Scene Examiner
* CSE Aviation's ICAO airline designator