IGF2BP2

IGF2BP2

Insulin-like growth factor 2 mRNA binding protein 2, also known as IGF2BP2, is a human gene.cite web | title = Entrez Gene: IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10644| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.cite web | title = Entrez Gene: IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10644| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yisraeli JK |title=VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins. |journal=Biol. Cell |volume=97 |issue= 1 |pages= 87–96 |year= 2005 |pmid= 15601260 |doi= 10.1042/BC20040151
*cite journal | author=Nielsen J, Christiansen J, Lykke-Andersen J, "et al." |title=A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development. |journal=Mol. Cell. Biol. |volume=19 |issue= 2 |pages= 1262–70 |year= 1999 |pmid= 9891060 |doi=
*cite journal | author=Zhang JY, Chan EK, Peng XX, Tan EM |title=A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma. |journal=J. Exp. Med. |volume=189 |issue= 7 |pages= 1101–10 |year= 1999 |pmid= 10190901 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Moraes KC, Quaresma AJ, Maehnss K, Kobarg J |title=Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D). |journal=Biol. Chem. |volume=384 |issue= 1 |pages= 25–37 |year= 2003 |pmid= 12674497 |doi=
*cite journal | author=Brants JR, Ayoubi TA, Chada K, "et al." |title=Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2. |journal=FEBS Lett. |volume=569 |issue= 1-3 |pages= 277–83 |year= 2004 |pmid= 15225648 |doi= 10.1016/j.febslet.2004.05.075
*cite journal | author=Ping S, Wang S, Zhang J, Peng X |title=Effect of all-trans-retinoic acid on mRNA binding protein p62 in human gastric cancer cells. |journal=Int. J. Biochem. Cell Biol. |volume=37 |issue= 3 |pages= 616–27 |year= 2005 |pmid= 15618018 |doi= 10.1016/j.biocel.2004.08.007
*cite journal | author=Hammer NA, Hansen TO, Byskov AG, "et al." |title=Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer. |journal=Reproduction |volume=130 |issue= 2 |pages= 203–12 |year= 2005 |pmid= 16049158 |doi= 10.1530/rep.1.00664
*cite journal | author=Natkunam Y, Vainer G, Chen J, "et al." |title=Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms. |journal=Haematologica |volume=92 |issue= 2 |pages= 176–83 |year= 2007 |pmid= 17296566 |doi=
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Cleynen I, Brants JR, Peeters K, "et al." |title=HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB. |journal=Mol. Cancer Res. |volume=5 |issue= 4 |pages= 363–72 |year= 2007 |pmid= 17426251 |doi= 10.1158/1541-7786.MCR-06-0331

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


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