PIWIL1

Piwi-like 1 (Drosophila), also known as PIWIL1, is a human gene.cite web | title = Entrez Gene: PIWIL1 piwi-like 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9271| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells.cite web | title = Entrez Gene: PIWIL1 piwi-like 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9271| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Cox DN, Chao A, Baker J, "et al." |title=A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. |journal=Genes Dev. |volume=12 |issue= 23 |pages= 3715–27 |year= 1999 |pmid= 9851978 |doi=
*cite journal | author=Sharma AK, Nelson MC, Brandt JE, "et al." |title=Human CD34(+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi. |journal=Blood |volume=97 |issue= 2 |pages= 426–34 |year= 2001 |pmid= 11154219 |doi=
*cite journal | author=Qiao D, Zeeman AM, Deng W, "et al." |title=Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. |journal=Oncogene |volume=21 |issue= 25 |pages= 3988–99 |year= 2002 |pmid= 12037681 |doi= 10.1038/sj.onc.1205505
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Sasaki T, Shiohama A, Minoshima S, Shimizu N |title=Identification of eight members of the Argonaute family in the human genome small star, filled. |journal=Genomics |volume=82 |issue= 3 |pages= 323–30 |year= 2004 |pmid= 12906857 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Tahbaz N, Kolb FA, Zhang H, "et al." |title=Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer. |journal=EMBO Rep. |volume=5 |issue= 2 |pages= 189–94 |year= 2004 |pmid= 14749716 |doi= 10.1038/sj.embor.7400070
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Liu X, Sun Y, Guo J, "et al." |title=Expression of hiwi gene in human gastric cancer was associated with proliferation of cancer cells. |journal=Int. J. Cancer |volume=118 |issue= 8 |pages= 1922–9 |year= 2006 |pmid= 16287078 |doi= 10.1002/ijc.21575
*cite journal | author=Taubert H, Greither T, Kaushal D, "et al." |title=Expression of the stem cell self-renewal gene Hiwi and risk of tumour-related death in patients with soft-tissue sarcoma. |journal=Oncogene |volume=26 |issue= 7 |pages= 1098–100 |year= 2007 |pmid= 16953229 |doi= 10.1038/sj.onc.1209880
*cite journal | author=Sugimoto K, Kage H, Aki N, "et al." |title=The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus. |journal=Biochem. Biophys. Res. Commun. |volume=359 |issue= 3 |pages= 497–502 |year= 2007 |pmid= 17544373 |doi= 10.1016/j.bbrc.2007.05.136

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