SNX3

Sorting nexin 3, also known as SNX3, is a human gene.cite web | title = Entrez Gene: SNX3 sorting nexin 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8724| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking.cite web | title = Entrez Gene: SNX3 sorting nexin 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8724| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Haft CR, de la Luz Sierra M, Barr VA, "et al." |title=Identification of a family of sorting nexin molecules and characterization of their association with receptors. |journal=Mol. Cell. Biol. |volume=18 |issue= 12 |pages= 7278–87 |year= 1998 |pmid= 9819414 |doi=
*cite journal | author=Parks WT, Frank DB, Huff C, "et al." |title=Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases. |journal=J. Biol. Chem. |volume=276 |issue= 22 |pages= 19332–9 |year= 2001 |pmid= 11279102 |doi= 10.1074/jbc.M100606200
*cite journal | author=Xu Y, Hortsman H, Seet L, "et al." |title=SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P. |journal=Nat. Cell Biol. |volume=3 |issue= 7 |pages= 658–66 |year= 2001 |pmid= 11433298 |doi= 10.1038/35083051
*cite journal | author=Vervoort VS, Viljoen D, Smart R, "et al." |title=Sorting nexin 3 (SNX3) is disrupted in a patient with a translocation t(6;13)(q21;q12) and microcephaly, microphthalmia, ectrodactyly, prognathism (MMEP) phenotype. |journal=J. Med. Genet. |volume=39 |issue= 12 |pages= 893–9 |year= 2003 |pmid= 12471201 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Kumar RA, Everman DB, Morgan CT, "et al." |title=Absence of mutations in NR2E1 and SNX3 in five patients with MMEP (microcephaly, microphthalmia, ectrodactyly, and prognathism) and related phenotypes. |journal=BMC Med. Genet. |volume=8 |issue= |pages= 48 |year= 2007 |pmid= 17655765 |doi= 10.1186/1471-2350-8-48

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