Thromb-X

Thromb-X

Thromb-X is a Belgian biotech company. It was founded by Professor Désiré Collen, an expert in cardiovascular disease, of the Katholieke Universiteit Leuven and head of the "VIB Departement of Transgene Technology and Gene Therapy, K.U.Leuven".

History

Thromb-X was founded in 1991, as a spin-off company of Katholieke Universiteit Leuven. The company was constituted jointly by K.U.Leuven R&D and Prof. Désiré Collen. In 1999 ThromboGenics Ltd., (Dublin, Ireland), became the majority shareholder of Thromb-X and Thromb-X became the R&D subsidiary of Thrombogenics.

Thromb-X was established to develop tissue plasminogen activator (tPA), a thrombolytic agent, as a treatment of acute myocardial infarction (heart attack) [Collen D, Billiau A, Edy J, De Somer P., Identification of the human plasma protein which inhibits fibrinolysis associated with malignant cells, Biochim Biophys Acta. 1977 Sep 29;499(2):194-201] [Collen D, Verstraete M. Systemic thrombolytic therapy of acute myocardial infarction? Circulation. 1983 Aug;68(2):462–465] [Collen D. Human tissue-type plasminogen activator: from the laboratory to the bedside. Circulation. 1985 Jul;72(1):18–20] [Collen D, Bounameaux H, De Cock F, Lijnen HR, Verstraete M., Analysis of coagulation and fibrinolysis during intravenous infusion of recombinant human tissue-type plasminogen activator in patients with acute myocardial infarction, Circulation. 1986 Mar;73(3):511–517] .

References

ource

* [http://www.drugresearcher.com/news/ng.asp?id=74190-thrombogenics-bioinvent-anticoagulant-tb-factor-viii Thrombogenics and Bioinvent trial anticoagulant]
* [http://www.flandersbio.be/organization_detail2.asp?id_org=43 Thromb-X]

External links

* [http://www.thrombogenics.com/ ThromboGenics]


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  • thromb- — thromb(o) ♦ Élément, du gr. thrombos « caillot ». ⇒THROMB(O) , (THROMB , THROMBO )élém. formant I. Élém. tiré du gr. « caillot, masse coagulée », latinisé en thrombus, entrant dans la constr. de termes sav. en méd. et biol. A. [Thromb(o) signifie …   Encyclopédie Universelle

  • thromb... — thromb..., Thromb... vgl. ↑thrombo..., Thrombo …   Das große Fremdwörterbuch

  • Thromb- — vor Konsonaten meist Thrombo [↑ Thrombus] Bestimmungswort von Zus. mit der Bed. »zur Blutgerinnung oder zu Thrombozyten gehörig« …   Universal-Lexikon

  • thromb... — thromb...,   Wortbildungselement, thrombo …   Universal-Lexikon

  • thromb[o]embolisch — thromb[o]|em|bo̱lisch: die Thromboembolie betreffend, zu ihr gehörend …   Das Wörterbuch medizinischer Fachausdrücke

  • thromb-endarterectomy — noun Etymologically incorrect Cate, WR, Scott, HW: Cerebral ischemia of central origin: Relief by subclavian vertebral artery thromb endarterectomy. Surgery, 45:19, 1959 …   Wiktionary

  • thromb- — or thrombo combining form Etymology: Greek thrombos clot blood clot ; clotting of blood < thrombin > < thromboplastic > …   New Collegiate Dictionary

  • thromb- — See thrombo . * * * (thrombo ) prefix denoting 1. a blood clot (thrombus). 2. thrombosis. 3. blood platelets …   Medical dictionary

  • thromb — thrombosis, thrombus …   Medical dictionary

  • thromb(o)- — [Gr. thrombos clot] a combining form denoting relationship to a clot, or thrombus …   Medical dictionary

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