FCRLA

Fc receptor-like A, also known as FCRLA, is a human gene.cite web | title = Entrez Gene: FCRLA Fc receptor-like A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84824| accessdate = ]

PBB_Summary
section_title =
summary_text = Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis. [supplied by OMIM] cite web | title = Entrez Gene: FCRLA Fc receptor-like A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84824| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Mechetina LV, Najakshin AM, Volkova OY, "et al." |title=FCRL, a novel member of the leukocyte Fc receptor family possesses unique structural features. |journal=Eur. J. Immunol. |volume=32 |issue= 1 |pages= 87–96 |year= 2002 |pmid= 11754007 |doi=
*cite journal | author=Facchetti F, Cella M, Festa S, "et al." |title=An unusual Fc receptor-related protein expressed in human centroblasts. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 6 |pages= 3776–81 |year= 2002 |pmid= 11891275 |doi= 10.1073/pnas.022042699
*cite journal | author=Davis RS, Li H, Chen CC, "et al." |title=Definition of an Fc receptor-related gene (FcRX) expressed in human and mouse B cells. |journal=Int. Immunol. |volume=14 |issue= 9 |pages= 1075–83 |year= 2003 |pmid= 12202404 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Huizinga TW, Ioan-Facsinay A |title=Soluble FcgammaRIIIa as a marker for rheumatoid arthritis: the use of genetics in selected populations to study pathogenetic pathways. |journal=J. Rheumatol. |volume=30 |issue= 9 |pages= 1904–6 |year= 2004 |pmid= 12966588 |doi=
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Inozume T, Matsuzaki Y, Kurihara S, "et al." |title=Novel melanoma antigen, FCRL/FREB, identified by cDNA profile comparison using DNA chip are immunogenic in multiple melanoma patients. |journal=Int. J. Cancer |volume=114 |issue= 2 |pages= 283–90 |year= 2005 |pmid= 15551350 |doi= 10.1002/ijc.20735
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Taylor AI, Gould HJ, Sutton BJ, Calvert RA |title=The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL. |journal=Immunogenetics |volume=59 |issue= 4 |pages= 323–8 |year= 2007 |pmid= 17273841 |doi= 10.1007/s00251-007-0195-9

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