BRCC3

BRCA1/BRCA2-containing complex, subunit 3, also known as BRCC3, is a human gene.cite web | title = Entrez Gene: BRCC3 BRCA1/BRCA2-containing complex, subunit 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79184| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This protein is also thought to be involved in the cellular response to ionizing radiation and progression through the G2/M checkpoint. Alternative splicing results in multiple transcript variants.cite web | title = Entrez Gene: BRCC3 BRCA1/BRCA2-containing complex, subunit 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79184| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kenwrick S, Levinson B, Taylor S, "et al." |title=Isolation and sequence of two genes associated with a CpG island 5' of the factor VIII gene. |journal=Hum. Mol. Genet. |volume=1 |issue= 3 |pages= 179–86 |year= 1993 |pmid= 1303175 |doi=
*cite journal | author=Fisch P, Forster A, Sherrington PD, "et al." |title=The chromosomal translocation t(X;14)(q28;q11) in T-cell pro-lymphocytic leukaemia breaks within one gene and activates another. |journal=Oncogene |volume=8 |issue= 12 |pages= 3271–6 |year= 1993 |pmid= 8247530 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Dong Y, Hakimi MA, Chen X, "et al." |title=Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. |journal=Mol. Cell |volume=12 |issue= 5 |pages= 1087–99 |year= 2004 |pmid= 14636569 |doi=
*cite journal | author=Ambroggio XI, Rees DC, Deshaies RJ |title=JAMM: a metalloprotease-like zinc site in the proteasome and signalosome. |journal=PLoS Biol. |volume=2 |issue= 1 |pages= E2 |year= 2006 |pmid= 14737182 |doi= 10.1371/journal.pbio.0020002
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139
*cite journal | author=Boudreau HE, Broustas CG, Gokhale PC, "et al." |title=Expression of BRCC3, a novel cell cycle regulated molecule, is associated with increased phospho-ERK and cell proliferation. |journal=Int. J. Mol. Med. |volume=19 |issue= 1 |pages= 29–39 |year= 2007 |pmid= 17143545 |doi=
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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