POLR3K

Polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa, also known as POLR3K, is a human gene.cite web | title = Entrez Gene: POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51728| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription.cite web | title = Entrez Gene: POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51728| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Jang KL, Collins MK, Latchman DS |title=The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC. |journal=J. Acquir. Immune Defic. Syndr. |volume=5 |issue= 11 |pages= 1142–7 |year= 1992 |pmid= 1403646 |doi=
*cite journal | author=Flint J, Thomas K, Micklem G, "et al." |title=The relationship between chromosome structure and function at a human telomeric region. |journal=Nat. Genet. |volume=15 |issue= 3 |pages= 252–7 |year= 1997 |pmid= 9054936 |doi= 10.1038/ng0397-252
*cite journal | author=Chédin S, Riva M, Schultz P, "et al." |title=The RNA cleavage activity of RNA polymerase III is mediated by an essential TFIIS-like subunit and is important for transcription termination. |journal=Genes Dev. |volume=12 |issue= 24 |pages= 3857–71 |year= 1999 |pmid= 9869639 |doi=
*cite journal | author=Spakovskiĭ GV, Lebedenko EN |title= [Molecular identification and characteristics of hRPC11, the smallest specific subunit of human RNA polymerase III] |journal=Bioorg. Khim. |volume=24 |issue= 11 |pages= 877–80 |year= 1999 |pmid= 10079944 |doi=
*cite journal | author=Daniels RJ, Peden JF, Lloyd C, "et al." |title=Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. |journal=Hum. Mol. Genet. |volume=10 |issue= 4 |pages= 339–52 |year= 2001 |pmid= 11157797 |doi=
*cite journal | author=Hu P, Wu S, Sun Y, "et al." |title=Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. |journal=Mol. Cell. Biol. |volume=22 |issue= 22 |pages= 8044–55 |year= 2002 |pmid= 12391170 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Martin J, Han C, Gordon LA, "et al." |title=The sequence and analysis of duplication-rich human chromosome 16. |journal=Nature |volume=432 |issue= 7020 |pages= 988–94 |year= 2005 |pmid= 15616553 |doi= 10.1038/nature03187
*cite journal | author=De Gobbi M, Viprakasit V, Hughes JR, "et al." |title=A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. |journal=Science |volume=312 |issue= 5777 |pages= 1215–7 |year= 2006 |pmid= 16728641 |doi= 10.1126/science.1126431
*cite journal | author=Johnson SS, Zhang C, Fromm J, "et al." |title=Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases. |journal=Mol. Cell |volume=26 |issue= 3 |pages= 367–79 |year= 2007 |pmid= 17499043 |doi= 10.1016/j.molcel.2007.03.021

PBB_Controls
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