CLEC1B

C-type lectin domain family 1, member B, also known as CLEC1B and CLEC-2, is a human gene.cite web | title = Entrez Gene: CLEC1B C-type lectin domain family 1, member B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51266| accessdate = ]

PBB_Summary
section_title =
summary_text = Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells. [supplied by OMIM] cite web | title = Entrez Gene: CLEC1B C-type lectin domain family 1, member B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51266| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Colonna M, Samaridis J, Angman L |title=Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells. |journal=Eur. J. Immunol. |volume=30 |issue= 2 |pages= 697–704 |year= 2000 |pmid= 10671229 |doi= 10.1002/1521-4141(200002)30:2<697::AID-IMMU697>3.0.CO;2-M |doilabel=10.1002/1521-4141(200002)30:2697::AID-IMMU6973.0.CO;2-M
*cite journal | author=Sobanov Y, Bernreiter A, Derdak S, "et al." |title=A novel cluster of lectin-like receptor genes expressed in monocytic, dendritic and endothelial cells maps close to the NK receptor genes in the human NK gene complex. |journal=Eur. J. Immunol. |volume=31 |issue= 12 |pages= 3493–503 |year= 2002 |pmid= 11745369 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Suzuki-Inoue K, Fuller GL, García A, "et al." |title=A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2. |journal=Blood |volume=107 |issue= 2 |pages= 542–9 |year= 2006 |pmid= 16174766 |doi= 10.1182/blood-2005-05-1994
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Watson AA, O'Callaghan CA |title=Crystallization and X-ray diffraction analysis of human CLEC-2. |journal=Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. |volume=61 |issue= Pt 12 |pages= 1094–6 |year= 2006 |pmid= 16511244 |doi= 10.1107/S1744309105037991
*cite journal | author=Scherer SE, Muzny DM, Buhay CJ, "et al." |title=The finished DNA sequence of human chromosome 12. |journal=Nature |volume=440 |issue= 7082 |pages= 346–51 |year= 2006 |pmid= 16541075 |doi= 10.1038/nature04569
*cite journal | author=Chaipan C, Soilleux EJ, Simpson P, "et al." |title=DC-SIGN and CLEC-2 mediate human immunodeficiency virus type 1 capture by platelets. |journal=J. Virol. |volume=80 |issue= 18 |pages= 8951–60 |year= 2006 |pmid= 16940507 |doi= 10.1128/JVI.00136-06
*cite journal | author=Watson AA, Brown J, Harlos K, "et al." |title=The crystal structure and mutational binding analysis of the extracellular domain of the platelet-activating receptor CLEC-2. |journal=J. Biol. Chem. |volume=282 |issue= 5 |pages= 3165–72 |year= 2007 |pmid= 17132623 |doi= 10.1074/jbc.M610383200
*cite journal | author=Suzuki-Inoue K, Kato Y, Inoue O, "et al." |title=Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells. |journal=J. Biol. Chem. |volume=282 |issue= 36 |pages= 25993–6001 |year= 2007 |pmid= 17616532 |doi= 10.1074/jbc.M702327200

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