MX2

"For the aircraft see MX2 (aircraft)"
Myxovirus (influenza virus) resistance 2 (mouse), also known as MX2, is a human gene.cite web | title = Entrez Gene: MX2 myxovirus (influenza virus) resistance 2 (mouse)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4600| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.cite web | title = Entrez Gene: MX2 myxovirus (influenza virus) resistance 2 (mouse)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4600| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Horisberger MA, McMaster GK, Zeller H, "et al." |title=Cloning and sequence analyses of cDNAs for interferon- and virus-induced human Mx proteins reveal that they contain putative guanine nucleotide-binding sites: functional study of the corresponding gene promoter. |journal=J. Virol. |volume=64 |issue= 3 |pages= 1171–81 |year= 1990 |pmid= 2154602 |doi=
*cite journal | author=Aebi M, Fäh J, Hurt N, "et al." |title=cDNA structures and regulation of two interferon-induced human Mx proteins. |journal=Mol. Cell. Biol. |volume=9 |issue= 11 |pages= 5062–72 |year= 1990 |pmid= 2481229 |doi=
*cite journal | author=Horisberger MA, Wathelet M, Szpirer J, "et al." |title=cDNA cloning and assignment to chromosome 21 of IFI-78K gene, the human equivalent of murine Mx gene. |journal=Somat. Cell Mol. Genet. |volume=14 |issue= 2 |pages= 123–31 |year= 1988 |pmid= 3162334 |doi=
*cite journal | author=Melén K, Keskinen P, Ronni T, "et al." |title=Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope. |journal=J. Biol. Chem. |volume=271 |issue= 38 |pages= 23478–86 |year= 1996 |pmid= 8798556 |doi=
*cite journal | author=al-Masri AN, Werfel T, Jakschies D, von Wussow P |title=Intracellular staining of Mx proteins in cells from peripheral blood, bone marrow and skin. |journal=MP, Mol. Pathol. |volume=50 |issue= 1 |pages= 9–14 |year= 1997 |pmid= 9208807 |doi=
*cite journal | author=Melén K, Julkunen I |title=Nuclear cotransport mechanism of cytoplasmic human MxB protein. |journal=J. Biol. Chem. |volume=272 |issue= 51 |pages= 32353–9 |year= 1998 |pmid= 9405443 |doi=
*cite journal | author=Hattori M, Fujiyama A, Taylor TD, "et al." |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Tanaka S, Honda Y, Honda M |title=Identification of differentially expressed genes in blood cells of narcolepsy patients. |journal=Sleep |volume=30 |issue= 8 |pages= 974–9 |year= 2007 |pmid= 17702266 |doi=

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