IFI6

Interferon, alpha-inducible protein 6, also known as IFI6, is a human gene.cite web | title = Entrez Gene: IFI6 interferon, alpha-inducible protein 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2537| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.cite web | title = Entrez Gene: IFI6 interferon, alpha-inducible protein 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2537| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Itzhaki JE, Barnett MA, MacCarthy AB, "et al." |title=Targeted breakage of a human chromosome mediated by cloned human telomeric DNA. |journal=Nat. Genet. |volume=2 |issue= 4 |pages= 283–7 |year= 1993 |pmid= 1303280 |doi= 10.1038/ng1292-283
*cite journal | author=Clauss IM, Wathelet MG, Szpirer J, "et al." |title=Chromosomal localization of two human genes inducible by interferons, double-stranded RNA, and viruses. |journal=Cytogenet. Cell Genet. |volume=53 |issue= 2-3 |pages= 166–8 |year= 1990 |pmid= 1695131 |doi=
*cite journal | author=Itzhaki JE, Porter AC |title=Targeted disruption of a human interferon-inducible gene detected by secretion of human growth hormone. |journal=Nucleic Acids Res. |volume=19 |issue= 14 |pages= 3835–42 |year= 1991 |pmid= 1713665 |doi=
*cite journal | author=Kelly JM, Porter AC, Chernajovsky Y, "et al." |title=Characterization of a human gene inducible by alpha- and beta-interferons and its expression in mouse cells. |journal=EMBO J. |volume=5 |issue= 7 |pages= 1601–6 |year= 1986 |pmid= 3017706 |doi=
*cite journal | author=Porter AC, Chernajovsky Y, Dale TC, "et al." |title=Interferon response element of the human gene 6-16. |journal=EMBO J. |volume=7 |issue= 1 |pages= 85–92 |year= 1988 |pmid= 3359997 |doi=
*cite journal | author=Friedman RL, Manly SP, McMahon M, "et al." |title=Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells. |journal=Cell |volume=38 |issue= 3 |pages= 745–55 |year= 1984 |pmid= 6548414 |doi=
*cite journal | author=Turri MG, Cuin KA, Porter AC |title=Characterisation of a novel minisatellite that provides multiple splice donor sites in an interferon-induced transcript. |journal=Nucleic Acids Res. |volume=23 |issue= 11 |pages= 1854–61 |year= 1995 |pmid= 7596809 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hofmann WA, Stojiljkovic L, Fuchsova B, "et al." |title=Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II. |journal=Nat. Cell Biol. |volume=6 |issue= 11 |pages= 1094–101 |year= 2004 |pmid= 15502823 |doi= 10.1038/ncb1182
*cite journal | author=Tahara E, Tahara H, Kanno M, "et al." |title=G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell. |journal=Cancer Immunol. Immunother. |volume=54 |issue= 8 |pages= 729–40 |year= 2005 |pmid= 15685448 |doi= 10.1007/s00262-004-0645-2

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