COX7A2

Cytochrome c oxidase subunit VIIa polypeptide 2 (liver), also known as COX7A2, is a human gene.cite web | title = Entrez Gene: COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1347| accessdate = ]

PBB_Summary
section_title =
summary_text = Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa and the polypeptide 2 is present in both muscle and nonmuscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, present in all tissues. This gene may have several pseudogenes.cite web | title = Entrez Gene: COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1347| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lenka N, Vijayasarathy C, Mullick J, Avadhani NG |title=Structural organization and transcription regulation of nuclear genes encoding the mammalian cytochrome c oxidase complex. |journal=Prog. Nucleic Acid Res. Mol. Biol. |volume=61 |issue= |pages= 309–44 |year= 1998 |pmid= 9752724 |doi=
*cite journal | author=Van Kuilenburg AB, Van Beeumen JJ, Van der Meer NM, Muijsers AO |title=Subunits VIIa,b,c of human cytochrome c oxidase. Identification of both 'heart-type' and 'liver-type' isoforms of subunit VIIa in human heart. |journal=Eur. J. Biochem. |volume=203 |issue= 1-2 |pages= 193–9 |year= 1992 |pmid= 1309697 |doi=
*cite journal | author=Arnaudo E, Hirano M, Seelan RS, "et al." |title=Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase. |journal=Gene |volume=119 |issue= 2 |pages= 299–305 |year= 1992 |pmid= 1327965 |doi=
*cite journal | author=Fabrizi GM, Rizzuto R, Nakase H, "et al." |title=Sequence of a cDNA specifying subunit VIIa of human cytochrome c oxidase. |journal=Nucleic Acids Res. |volume=17 |issue= 17 |pages= 7107 |year= 1989 |pmid= 2550906 |doi=
*cite journal | author=Taanman JW, Hall RE, Tang C, "et al." |title=Tissue distribution of cytochrome c oxidase isoforms in mammals. Characterization with monoclonal and polyclonal antibodies. |journal=Biochim. Biophys. Acta |volume=1225 |issue= 1 |pages= 95–100 |year= 1993 |pmid= 8241294 |doi=
*cite journal | author=Merante F, Duncan AM, Mitchell G, "et al." |title=Chromosomal localization of the human liver form cytochrome c oxidase subunit VIIa gene. |journal=Genome |volume=40 |issue= 3 |pages= 318–24 |year= 1997 |pmid= 9202412 |doi=
*cite journal | author=Merante F, Ling M, Duncan AM, "et al." |title=Cloning, characterization, and chromosomal localization of human liver form cytochrome c oxidase subunit VIa related genes. |journal=Genome |volume=40 |issue= 3 |pages= 325–31 |year= 1997 |pmid= 9202413 |doi=
*cite journal | author=Hüttemann M, Mühlenbein N, Schmidt TR, "et al." |title=Isolation and sequence of the human cytochrome c oxidase subunit VIIaL gene. |journal=Biochim. Biophys. Acta |volume=1492 |issue= 1 |pages= 252–8 |year= 2000 |pmid= 11004498 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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