CORIN

CORIN

Corin, serine peptidase, also known as CORIN, is a human gene.cite web | title = Entrez Gene: CORIN corin, serine peptidase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10699| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.cite web | title = Entrez Gene: CORIN corin, serine peptidase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10699| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yan W, Sheng N, Seto M, "et al." |title=Corin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart. |journal=J. Biol. Chem. |volume=274 |issue= 21 |pages= 14926–35 |year= 1999 |pmid= 10329693 |doi=
*cite journal | author=Yan W, Wu F, Morser J, Wu Q |title=Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 15 |pages= 8525–9 |year= 2000 |pmid= 10880574 |doi= 10.1073/pnas.150149097
*cite journal | author=Hooper JD, Scarman AL, Clarke BE, "et al." |title=Localization of the mosaic transmembrane serine protease corin to heart myocytes. |journal=Eur. J. Biochem. |volume=267 |issue= 23 |pages= 6931–7 |year= 2001 |pmid= 11082206 |doi=
*cite journal | author=Wu F, Yan W, Pan J, "et al." |title=Processing of pro-atrial natriuretic peptide by corin in cardiac myocytes. |journal=J. Biol. Chem. |volume=277 |issue= 19 |pages= 16900–5 |year= 2002 |pmid= 11884416 |doi= 10.1074/jbc.M201503200
*cite journal | author=Pan J, Hinzmann B, Yan W, "et al." |title=Genomic structures of the human and murine corin genes and functional GATA elements in their promoters. |journal=J. Biol. Chem. |volume=277 |issue= 41 |pages= 38390–8 |year= 2002 |pmid= 12154094 |doi= 10.1074/jbc.M205686200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Knappe S, Wu F, Masikat MR, "et al." |title=Functional analysis of the transmembrane domain and activation cleavage of human corin: design and characterization of a soluble corin. |journal=J. Biol. Chem. |volume=278 |issue= 52 |pages= 52363–70 |year= 2004 |pmid= 14559895 |doi= 10.1074/jbc.M309991200
*cite journal | author=Knappe S, Wu F, Madlansacay MR, Wu Q |title=Identification of domain structures in the propeptide of corin essential for the processing of proatrial natriuretic peptide. |journal=J. Biol. Chem. |volume=279 |issue= 33 |pages= 34464–71 |year= 2004 |pmid= 15192093 |doi= 10.1074/jbc.M405041200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Dries DL, Victor RG, Rame JE, "et al." |title=Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension. |journal=Circulation |volume=112 |issue= 16 |pages= 2403–10 |year= 2006 |pmid= 16216958 |doi= 10.1161/CIRCULATIONAHA.105.568881
*cite journal | author=Rame JE, Drazner MH, Post W, "et al." |title=Corin I555(P568) allele is associated with enhanced cardiac hypertrophic response to increased systemic afterload. |journal=Hypertension |volume=49 |issue= 4 |pages= 857–64 |year= 2007 |pmid= 17296875 |doi= 10.1161/01.HYP.0000258566.95867.9e
*cite journal | author=Liao X, Wang W, Chen S, Wu Q |title=Role of glycosylation in corin zymogen activation. |journal=J. Biol. Chem. |volume=282 |issue= 38 |pages= 27728–35 |year= 2007 |pmid= 17660514 |doi= 10.1074/jbc.M703687200

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