- SPEG
SPEG complex locus, also known as SPEG, is a human
gene .cite web | title = Entrez Gene: SPEG SPEG complex locus| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10290| accessdate = ]PBB_Summary
section_title =
summary_text = Expression of this gene is thought to serve as a marker for differentiated vascular smooth muscle cells which may have a role in regulating growth and differentiation of this cell type. The encoded protein is highly similar to the corresponding rat and mouse proteins. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of only one variant has been defined.cite web | title = Entrez Gene: SPEG SPEG complex locus| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10290| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Hsieh CM, Yoshizumi M, Endege WO, "et al." |title=APEG-1, a novel gene preferentially expressed in aortic smooth muscle cells, is down-regulated by vascular injury. |journal=J. Biol. Chem. |volume=271 |issue= 29 |pages= 17354–9 |year= 1996 |pmid= 8663449 |doi=
*cite journal | author=Hsieh CM, Yet SF, Layne MD, "et al." |title=Genomic cloning and promoter analysis of aortic preferentially expressed gene-1. Identification of a vascular smooth muscle-specific promoter mediated by an E box motif. |journal=J. Biol. Chem. |volume=274 |issue= 20 |pages= 14344–51 |year= 1999 |pmid= 10318857 |doi=
*cite journal | author=Nagase T, Kikuno R, Ishikawa KI, "et al." |title=Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 1 |pages= 65–73 |year= 2000 |pmid= 10718198 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Sutter SB, Raeker MO, Borisov AB, Russell MW |title=Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases. |journal=Dev. Genes Evol. |volume=214 |issue= 7 |pages= 352–9 |year= 2005 |pmid= 15185077 |doi= 10.1007/s00427-004-0413-5
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Arvanitis DA, Flouris GA, Spandidos DA |title=Genomic rearrangements on VCAM1, SELE, APEG1and AIF1 loci in atherosclerosis. |journal=J. Cell. Mol. Med. |volume=9 |issue= 1 |pages= 153–9 |year= 2005 |pmid= 15784173 |doi=
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Manjasetty BA, Niesen FH, Scheich C, "et al." |title=X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1). |journal=BMC Struct. Biol. |volume=5 |issue= |pages= 21 |year= 2006 |pmid= 16354304 |doi= 10.1186/1472-6807-5-21
*cite journal | author=Tam JL, Triantaphyllopoulos K, Todd H, "et al." |title=The human desmin locus: gene organization and LCR-mediated transcriptional control. |journal=Genomics |volume=87 |issue= 6 |pages= 733–46 |year= 2006 |pmid= 16545539 |doi= 10.1016/j.ygeno.2006.01.009PBB_Controls
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