AKAP6

A kinase (PRKA) anchor protein 6, also known as AKAP6, is a human gene.cite web | title = Entrez Gene: AKAP6 A kinase (PRKA) anchor protein 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9472| accessdate = ]

PBB_Summary
section_title =
summary_text = The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum.cite web | title = Entrez Gene: AKAP6 A kinase (PRKA) anchor protein 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9472| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lester LB, Scott JD |title=Anchoring and scaffold proteins for kinases and phosphatases. |journal=Recent Prog. Horm. Res. |volume=52 |issue= |pages= 409–29; discussion 429–30 |year= 1997 |pmid= 9238861 |doi=
*cite journal | author=Michel JJ, Scott JD |title=AKAP mediated signal transduction. |journal=Annu. Rev. Pharmacol. Toxicol. |volume=42 |issue= |pages= 235–57 |year= 2002 |pmid= 11807172 |doi= 10.1146/annurev.pharmtox.42.083101.135801
*cite journal | author=Nakajima D, Okazaki N, Yamakawa H, "et al." |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=
*cite journal | author=McCartney S, Little BM, Langeberg LK, Scott JD |title=Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum. |journal=J. Biol. Chem. |volume=270 |issue= 16 |pages= 9327–33 |year= 1995 |pmid= 7721854 |doi=
*cite journal | author=Nagase T, Ishikawa K, Nakajima D, "et al." |title=Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=4 |issue= 2 |pages= 141–50 |year= 1997 |pmid= 9205841 |doi=
*cite journal | author=Kapiloff MS, Schillace RV, Westphal AM, Scott JD |title=mAK

*cite journal | author=Marx SO, Reiken S, Hisamatsu Y, "et al." |title=PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. |journal=Cell |volume=101 |issue= 4 |pages= 365–76 |year= 2000 |pmid= 10830164 |doi=
*cite journal | author=Dodge KL, Khouangsathiene S, Kapiloff MS, "et al." |title=mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. |journal=EMBO J. |volume=20 |issue= 8 |pages= 1921–30 |year= 2001 |pmid= 11296225 |doi= 10.1093/emboj/20.8.1921
*cite journal | author=Marx SO, Reiken S, Hisamatsu Y, "et al." |title=Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers. |journal=J. Cell Biol. |volume=153 |issue= 4 |pages= 699–708 |year= 2001 |pmid= 11352932 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Schulze DH, Muqhal M, Lederer WJ, Ruknudin AM |title=Sodium/calcium exchanger (NCX1) macromolecular complex. |journal=J. Biol. Chem. |volume=278 |issue= 31 |pages= 28849–55 |year= 2003 |pmid= 12754202 |doi= 10.1074/jbc.M300754200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285

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