WDR57

WD repeat domain 57 (U5 snRNP specific), also known as WDR57, is a gene found in many organisms, including, but not limited to Homo sapiens, Gallus gallus, Pan troglodytes, Canus lupus familiaris, Bos taurus, Mus musculus, and Rattus norvegicus.cite web | title = Entrez Gene: WDR57 WD repeat domain 57 (U5 snRNP specific)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9410| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs.cite web | title = Entrez Gene: WDR57 WD repeat domain 57 (U5 snRNP specific)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9410| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Turner IA, Norman CM, Churcher MJ, Newman AJ |title=Roles of the U5 snRNP in spliceosome dynamics and catalysis. |journal=Biochem. Soc. Trans. |volume=32 |issue= Pt 6 |pages= 928–31 |year= 2005 |pmid= 15506927 |doi= 10.1042/BST0320928
*cite journal | author=Neubauer G, King A, Rappsilber J, "et al." |title=Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. |journal=Nat. Genet. |volume=20 |issue= 1 |pages= 46–50 |year= 1998 |pmid= 9731529 |doi= 10.1038/1700
*cite journal | author=Achsel T, Ahrens K, Brahms H, "et al." |title=The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein. |journal=Mol. Cell. Biol. |volume=18 |issue= 11 |pages= 6756–66 |year= 1998 |pmid= 9774689 |doi=
*cite journal | author=Makarov EM, Makarova OV, Achsel T, Lührmann R |title=The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. |journal=J. Mol. Biol. |volume=298 |issue= 4 |pages= 567–75 |year= 2000 |pmid= 10788320 |doi= 10.1006/jmbi.2000.3685
*cite journal | author=Jurica MS, Licklider LJ, Gygi SR, "et al." |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Jordanova A, Irobi J, Thomas FP, "et al." |title=Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. |journal=Nat. Genet. |volume=38 |issue= 2 |pages= 197–202 |year= 2006 |pmid= 16429158 |doi= 10.1038/ng1727
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Liu S, Rauhut R, Vornlocher HP, Lührmann R |title=The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP. |journal=RNA |volume=12 |issue= 7 |pages= 1418–30 |year= 2006 |pmid= 16723661 |doi= 10.1261/rna.55406
*cite journal | author=Higa LA, Wu M, Ye T, "et al." |title=CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation. |journal=Nat. Cell Biol. |volume=8 |issue= 11 |pages= 1277–83 |year= 2006 |pmid= 17041588 |doi= 10.1038/ncb1490
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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