- IFT88
Intraflagellar transport 88 homolog (Chlamydomonas), also known as IFT88, is a human
gene .cite web | title = Entrez Gene: IFT88 intraflagellar transport 88 homolog (Chlamydomonas)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8100| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene.cite web | title = Entrez Gene: IFT88 intraflagellar transport 88 homolog (Chlamydomonas)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8100| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Murcia NS, Sweeney WE, Avner ED |title=New insights into the molecular pathophysiology of polycystic kidney disease. |journal=Kidney Int. |volume=55 |issue= 4 |pages= 1187–97 |year= 1999 |pmid= 10200981 |doi= 10.1046/j.1523-1755.1999.00370.x
*cite journal | author=Schrick JJ, Onuchic LF, Reeders ST, "et al." |title=Characterization of the human homologue of the mouse Tg737 candidate polycystic kidney disease gene. |journal=Hum. Mol. Genet. |volume=4 |issue= 4 |pages= 559–67 |year= 1995 |pmid= 7633404 |doi=
*cite journal | author=Moyer JH, Lee-Tischler MJ, Kwon HY, "et al." |title=Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. |journal=Science |volume=264 |issue= 5163 |pages= 1329–33 |year= 1994 |pmid= 8191288 |doi=
*cite journal | author=Onuchic LF, Schrick JJ, Ma J, "et al." |title=Sequence analysis of the human hTg737 gene and its polymorphic sites in patients with autosomal recessive polycystic kidney disease. |journal=Mamm. Genome |volume=6 |issue= 11 |pages= 805–8 |year= 1996 |pmid= 8597639 |doi=
*cite journal | author=Isfort RJ, Cody DB, Doersen CJ, "et al." |title=The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene. |journal=Oncogene |volume=15 |issue= 15 |pages= 1797–803 |year= 1997 |pmid= 9362446 |doi= 10.1038/sj.onc.1201535
*cite journal | author=Bonura C, Paterlini-Brechot P, Brechot C |title=Structure and expression of Tg737, a putative tumor suppressor gene, in human hepatocellular carcinomas. |journal=Hepatology |volume=30 |issue= 3 |pages= 677–81 |year= 1999 |pmid= 10462374 |doi= 10.1002/hep.510300325
*cite journal | author=Taulman PD, Haycraft CJ, Balkovetz DF, Yoder BK |title=Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. |journal=Mol. Biol. Cell |volume=12 |issue= 3 |pages= 589–99 |year= 2001 |pmid= 11251073 |doi=
*cite journal | author=Harrington JJ, Sherf B, Rundlett S, "et al." |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440–5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Lehner B, Semple JI, Brown SE, "et al." |title=Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. |journal=Genomics |volume=83 |issue= 1 |pages= 153–67 |year= 2004 |pmid= 14667819 |doi=
*cite journal | author=Khanna H, Hurd TW, Lillo C, "et al." |title=RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins. |journal=J. Biol. Chem. |volume=280 |issue= 39 |pages= 33580–7 |year= 2005 |pmid= 16043481 |doi= 10.1074/jbc.M505827200
*cite journal | author=Robert A, Margall-Ducos G, Guidotti JE, "et al." |title=The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells. |journal=J. Cell. Sci. |volume=120 |issue= Pt 4 |pages= 628–37 |year= 2007 |pmid= 17264151 |doi= 10.1242/jcs.03366PBB_Controls
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