- CCT3
Chaperonin containing TCP1, subunit 3 (gamma), also known as CCT3, is a human
gene .cite web | title = Entrez Gene: CCT3 chaperonin containing TCP1, subunit 3 (gamma)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7203| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.cite web | title = Entrez Gene: CCT3 chaperonin containing TCP1, subunit 3 (gamma)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7203| accessdate = ]References
Further reading
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citations =
*cite journal | author=Kubota H, Hynes G, Carne A, "et al." |title=Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. |journal=Curr. Biol. |volume=4 |issue= 2 |pages= 89–99 |year= 1994 |pmid= 7953530 |doi=
*cite journal | author=Sévigny G, Joly EC, Bibor-Hardy V, Lemieux N |title=Assignment of the human homologue of the mTRiC-P5 gene (TRIC5) to band 1q23 by fluorescence in situ hybridization. |journal=Genomics |volume=22 |issue= 3 |pages= 634–6 |year= 1995 |pmid= 8001976 |doi=
*cite journal | author=Joly EC, Sévigny G, Todorov IT, Bibor-Hardy V |title=cDNA encoding a novel TCP1-related protein. |journal=Biochim. Biophys. Acta |volume=1217 |issue= 2 |pages= 224–6 |year= 1994 |pmid= 8110840 |doi=
*cite journal | author=Walkley NA, Demaine AG, Malik AN |title=Cloning, structure and mRNA expression of human Cctg, which encodes the chaperonin subunit CCT gamma. |journal=Biochem. J. |volume=313 ( Pt 2) |issue= |pages= 381–9 |year= 1996 |pmid= 8573069 |doi=
*cite journal | author=Feldman DE, Thulasiraman V, Ferreyra RG, Frydman J |title=Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC. |journal=Mol. Cell |volume=4 |issue= 6 |pages= 1051–61 |year= 2000 |pmid= 10635329 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Wong N, Chan A, Lee SW, "et al." |title=Positional mapping for amplified DNA sequences on 1q21-q22 in hepatocellular carcinoma indicates candidate genes over-expression. |journal=J. Hepatol. |volume=38 |issue= 3 |pages= 298–306 |year= 2003 |pmid= 12586295 |doi=
*cite journal | author=Yuryev A, Wennogle LP |title=Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis. |journal=Genomics |volume=81 |issue= 2 |pages= 112–25 |year= 2003 |pmid= 12620389 |doi=
*cite journal | author=Reuter TY, Medhurst AL, Waisfisz Q, "et al." |title=Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport. |journal=Exp. Cell Res. |volume=289 |issue= 2 |pages= 211–21 |year= 2003 |pmid= 14499622 |doi=
*cite journal | author=Imai Y, Soda M, Murakami T, "et al." |title=A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. |journal=J. Biol. Chem. |volume=278 |issue= 51 |pages= 51901–10 |year= 2004 |pmid= 14532270 |doi= 10.1074/jbc.M309655200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727PBB_Controls
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