EXOC1

Exocyst complex component 1, also known as EXOC1, is a human gene.cite web | title = Entrez Gene: EXOC1 exocyst complex component 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55763| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.cite web | title = Entrez Gene: EXOC1 exocyst complex component 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55763| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hsu SC, TerBush D, Abraham M, Guo W |title=The exocyst complex in polarized exocytosis. |journal=Int. Rev. Cytol. |volume=233 |issue= |pages= 243–65 |year= 2004 |pmid= 15037366 |doi= 10.1016/S0074-7696(04)33006-8
*cite journal | author=Kee Y, Yoo JS, Hazuka CD, "et al." |title=Subunit structure of the mammalian exocyst complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 26 |pages= 14438–43 |year= 1998 |pmid= 9405631 |doi=
*cite journal | author=Hsu SC, Hazuka CD, Roth R, "et al." |title=Subunit composition, protein interactions, and structures of the mammalian brain sec6/8 complex and septin filaments. |journal=Neuron |volume=20 |issue= 6 |pages= 1111–22 |year= 1998 |pmid= 9655500 |doi=
*cite journal | author=Zhang QH, Ye M, Wu XY, "et al." |title=Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. |journal=Genome Res. |volume=10 |issue= 10 |pages= 1546–60 |year= 2001 |pmid= 11042152 |doi=
*cite journal | author=Brymora A, Valova VA, Larsen MR, "et al." |title=The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene. |journal=J. Biol. Chem. |volume=276 |issue= 32 |pages= 29792–7 |year= 2001 |pmid= 11406615 |doi= 10.1074/jbc.C100320200
*cite journal | author=Matern HT, Yeaman C, Nelson WJ, Scheller RH |title=The Sec6/8 complex in mammalian cells: characterization of mammalian Sec3, subunit interactions, and expression of subunits in polarized cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 17 |pages= 9648–53 |year= 2001 |pmid= 11493706 |doi= 10.1073/pnas.171317898
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Inoue M, Chang L, Hwang J, "et al." |title=The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin. |journal=Nature |volume=422 |issue= 6932 |pages= 629–33 |year= 2003 |pmid= 12687004 |doi= 10.1038/nature01533
*cite journal | author=Moskalenko S, Tong C, Rosse C, "et al." |title=Ral GTPases regulate exocyst assembly through dual subunit interactions. |journal=J. Biol. Chem. |volume=278 |issue= 51 |pages= 51743–8 |year= 2004 |pmid= 14525976 |doi= 10.1074/jbc.M308702200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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