HOOK1

HOOK1

Hook homolog 1 (Drosophila), also known as HOOK1, is a human gene.cite web | title = Entrez Gene: HOOK1 hook homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51361| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.cite web | title = Entrez Gene: HOOK1 hook homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51361| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Krämer H, Phistry M |title=Genetic analysis of hook, a gene required for endocytic trafficking in drosophila. |journal=Genetics |volume=151 |issue= 2 |pages= 675–84 |year= 1999 |pmid= 9927460 |doi=
*cite journal | author=Walenta JH, Didier AJ, Liu X, Krämer H |title=The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins. |journal=J. Cell Biol. |volume=152 |issue= 5 |pages= 923–34 |year= 2001 |pmid= 11238449 |doi=
*cite journal | author=Mendoza-Lujambio I, Burfeind P, Dixkens C, "et al." |title=The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse. |journal=Hum. Mol. Genet. |volume=11 |issue= 14 |pages= 1647–58 |year= 2003 |pmid= 12075009 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Luiro K, Yliannala K, Ahtiainen L, "et al." |title=Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway. |journal=Hum. Mol. Genet. |volume=13 |issue= 23 |pages= 3017–27 |year= 2005 |pmid= 15471887 |doi= 10.1093/hmg/ddh321
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Weimer JM, Chattopadhyay S, Custer AW, Pearce DA |title=Elevation of Hook1 in a disease model of Batten disease does not affect a novel interaction between Ankyrin G and Hook1. |journal=Biochem. Biophys. Res. Commun. |volume=330 |issue= 4 |pages= 1176–81 |year= 2005 |pmid= 15823567 |doi= 10.1016/j.bbrc.2005.03.103
*cite journal | author=Simpson F, Martin S, Evans TM, "et al." |title=A novel hook-related protein family and the characterization of hook-related protein 1. |journal=Traffic |volume=6 |issue= 6 |pages= 442–58 |year= 2005 |pmid= 15882442 |doi= 10.1111/j.1600-0854.2005.00289.x
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

PBB_Controls
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Look at other dictionaries:

  • hook — hook1 hookless, adj. hooklike, adj. /hook/, n. 1. a curved or angular piece of metal or other hard substance for catching, pulling, holding, or suspending something. 2. a fishhook. 3. anything that catches; snare; trap. 4. something that attracts …   Universalium

  • hook — hook1 S3 [huk] n ▬▬▬▬▬▬▬ 1¦(hanging things)¦ 2¦(catching fish)¦ 3 let/get somebody off the hook 4 leave/take the phone off the hook 5 be ringing off the hook 6¦(interest)¦ 7 by hook or by crook 8¦(hitting somebody)¦ 9 h …   Dictionary of contemporary English

  • hook — hook1 [ huk ] noun count ** 1. ) a curved piece of metal or plastic for hanging things on: He hung his coat on a hook on the back of the door. a ) a small curved piece of metal or plastic used for catching fish at the end of a LINE b ) a curved… …   Usage of the words and phrases in modern English

  • hooker — hooker1 /hook euhr/, n. 1. a person or thing that hooks. 2. Slang. prostitute. 3. Slang. a large drink of liquor. 4. Slang. a concealed problem, flaw, or drawback; a catch. 5. Rugby. a player who hooks the ball in the front line of scrummage. 6.… …   Universalium

  • hooked — hookedness /hoohk id nis/, n. /hookt/, adj. 1. bent like a hook; hook shaped. 2. having a hook or hooks. 3. made with a hook or by hooking. 4. Informal. a. addicted to narcotic drugs. b. slavishly interested in, devoted to, or obsessed with: He… …   Universalium

  • hooknose — hooknosed, adj. /hook nohz /, n. a curved nose; aquiline nose. [1680 90; HOOK1 + NOSE] * * * …   Universalium

  • hookswinging — /hook swing ing/, n. a ritualistic torture, practiced among the Mandan Indians, in which a voluntary victim was suspended from hooks attached to the flesh of the back. [1890 95; HOOK1 + SWING1 + ING1] * * * …   Universalium

  • hooktender — /hook ten deuhr/, n. (in lumbering) the supervisor of a rigging crew. [1905 10; HOOK1 + TENDER3] * * * …   Universalium

  • hookworm — hookwormy, adj. /hook werrm /, n. 1. any of certain bloodsucking nematode worms, as Ancylostoma duodenale and Necator americanus, parasitic in the intestine of humans and other animals. 2. Also called hookworm disease. a disease caused by… …   Universalium

  • hooky — hooky1 /hook ee/, n. unjustifiable absence from school, work, etc. (usually used in the phrase play hooky): On the first warm spring day the boys played hooky to go fishing. Also, hookey. [1840 50, Amer.; perh. alter. of phrase hook it escape,… …   Universalium

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