INSL4

Insulin-like 4 (placenta), also known as INSL4, is a human gene.cite web | title = Entrez Gene: INSL4 insulin-like 4 (placenta)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3641| accessdate = ]

PBB_Summary
section_title =
summary_text = INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast.cite web | title = Entrez Gene: INSL4 insulin-like 4 (placenta)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3641| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Chassin D, Laurent A, Janneau JL, "et al." |title=Cloning of a new member of the insulin gene superfamily (INSL4) expressed in human placenta. |journal=Genomics |volume=29 |issue= 2 |pages= 465–70 |year= 1996 |pmid= 8666396 |doi= 10.1006/geno.1995.9980
*cite journal | author=Koman A, Cazaubon S, Couraud PO, "et al." |title=Molecular characterization and in vitro biological activity of placentin, a new member of the insulin gene family. |journal=J. Biol. Chem. |volume=271 |issue= 34 |pages= 20238–41 |year= 1996 |pmid= 8702754 |doi=
*cite journal | author=Bellet D, Lavaissiere L, Mock P, "et al." |title=Identification of pro-EPIL and EPIL peptides translated from insulin-like 4 (INSL4) mRNA in human placenta. |journal=J. Clin. Endocrinol. Metab. |volume=82 |issue= 9 |pages= 3169–72 |year= 1997 |pmid= 9284764 |doi=
*cite journal | author=Veitia R, Laurent A, Quintana-Murci L, "et al." |title=The INSL4 gene maps close to WI-5527 at 9p24.1-->p23.3 clustered with two relaxin genes and outside the critical region for the monosomy 9p syndrome. |journal=Cytogenet. Cell Genet. |volume=81 |issue= 3-4 |pages= 275–7 |year= 1998 |pmid= 9730618 |doi=
*cite journal | author=Laurent A, Rouillac C, Delezoide AL, "et al." |title=Insulin-like 4 (INSL4) gene expression in human embryonic and trophoblastic tissues. |journal=Mol. Reprod. Dev. |volume=51 |issue= 2 |pages= 123–9 |year= 1999 |pmid= 9740319 |doi= 10.1002/(SICI)1098-2795(199810)51:2<123::AID-MRD1>3.0.CO;2-S |doilabel=10.1002/(SICI)1098-2795(199810)51:2123::AID-MRD13.0.CO;2-S
*cite journal | author=Janneau JL, Maldonado-Estrada J, Tachdjian G, "et al." |title=Transcriptional expression of genes involved in cell invasion and migration by normal and tumoral trophoblast cells. |journal=J. Clin. Endocrinol. Metab. |volume=87 |issue= 11 |pages= 5336–9 |year= 2002 |pmid= 12414911 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bièche I, Laurent A, Laurendeau I, "et al." |title=Placenta-specific INSL4 expression is mediated by a human endogenous retrovirus element. |journal=Biol. Reprod. |volume=68 |issue= 4 |pages= 1422–9 |year= 2004 |pmid= 12606452 |doi= 10.1095/biolreprod.102.010322
*cite journal | author=Humphray SJ, Oliver K, Hunt AR, "et al." |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465
*cite journal | author=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Millar L, Streiner N, Webster L, "et al." |title=Early placental insulin-like protein (INSL4 or EPIL) in placental and fetal membrane growth. |journal=Biol. Reprod. |volume=73 |issue= 4 |pages= 695–702 |year= 2006 |pmid= 15958731 |doi= 10.1095/biolreprod.105.039859

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