L3MBTL

L(3)mbt-like (Drosophila), also known as L3MBTL, is a human gene.cite web | title = Entrez Gene: L3MBTL l(3)mbt-like (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26013| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.cite web | title = Entrez Gene: L3MBTL l(3)mbt-like (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26013| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Trojer P, Li G, Sims RJ, "et al." |title=L3MBTL1, a histone-methylation-dependent chromatin lock. |journal=Cell |volume=129 |issue= 5 |pages= 915–28 |year= 2007 |pmid= 17540172 |doi= 10.1016/j.cell.2007.03.048
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=MacGrogan D, Kalakonda N, Alvarez S, "et al." |title=Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells. |journal=Genes Chromosomes Cancer |volume=41 |issue= 3 |pages= 203–13 |year= 2004 |pmid= 15334543 |doi= 10.1002/gcc.20087
*cite journal | author=Li J, Bench AJ, Vassiliou GS, "et al." |title=Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 19 |pages= 7341–6 |year= 2004 |pmid= 15123827 |doi= 10.1073/pnas.0308195101
*cite journal | author=Wang WK, Tereshko V, Boccuni P, "et al." |title=Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets. |journal=Structure |volume=11 |issue= 7 |pages= 775–89 |year= 2004 |pmid= 12842041 |doi=
*cite journal | author=Boccuni P, MacGrogan D, Scandura JM, Nimer SD |title=The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6). |journal=J. Biol. Chem. |volume=278 |issue= 17 |pages= 15412–20 |year= 2003 |pmid= 12588862 |doi= 10.1074/jbc.M300592200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Fossey SC, Mychaleckyj JC, Pendleton JK, "et al." |title=A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20. |journal=Genomics |volume=76 |issue= 1-3 |pages= 45–57 |year= 2001 |pmid= 11549316 |doi= 10.1006/geno.2001.6584
*cite journal | author=Dias Neto E, Correa RG, Verjovski-Almeida S, "et al." |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=
*cite journal | author=Koga H, Matsui S, Hirota T, "et al." |title=A human homolog of Drosophila lethal(3)malignant brain tumor (l(3)mbt) protein associates with condensed mitotic chromosomes. |journal=Oncogene |volume=18 |issue= 26 |pages= 3799–809 |year= 1999 |pmid= 10445843 |doi= 10.1038/sj.onc.1202732
*cite journal | author=Ishikawa K, Nagase T, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 3 |pages= 169–76 |year= 1998 |pmid= 9734811 |doi=

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