PPRC1

PPRC1

Peroxisome proliferator-activated receptor gamma, coactivator-related 1, also known as PPRC1, is a human gene.cite web | title = Entrez Gene: PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23082| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPARGC1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals.cite web | title = Entrez Gene: PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23082| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Finck BN, Kelly DP |title=PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. |journal=J. Clin. Invest. |volume=116 |issue= 3 |pages= 615–22 |year= 2006 |pmid= 16511594 |doi= 10.1172/JCI27794
*cite journal | author=Yamagata K, Yoshimochi K, Daitoku H, "et al." |title=Bile acid represses the peroxisome proliferator-activated receptor-gamma coactivator-1 promoter activity in a small heterodimer partner-dependent manner. |journal=Int. J. Mol. Med. |volume=19 |issue= 5 |pages= 751–6 |year= 2007 |pmid= 17390079 |doi=
*cite journal | author=Srivastava S, Barrett JN, Moraes CT |title=PGC-1alpha/beta upregulation is associated with improved oxidative phosphorylation in cells harboring nonsense mtDNA mutations. |journal=Hum. Mol. Genet. |volume=16 |issue= 8 |pages= 993–1005 |year= 2007 |pmid= 17341490 |doi= 10.1093/hmg/ddm045
*cite journal | author=Gleyzer N, Vercauteren K, Scarpulla RC |title=Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators. |journal=Mol. Cell. Biol. |volume=25 |issue= 4 |pages= 1354–66 |year= 2005 |pmid= 15684387 |doi= 10.1128/MCB.25.4.1354-1366.2005
*cite journal | author=Yamamoto T, Shimano H, Nakagawa Y, "et al." |title=SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes. |journal=J. Biol. Chem. |volume=279 |issue= 13 |pages= 12027–35 |year= 2004 |pmid= 14722127 |doi= 10.1074/jbc.M310333200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Savagner F, Mirebeau D, Jacques C, "et al." |title=PGC-1-related coactivator and targets are upregulated in thyroid oncocytoma. |journal=Biochem. Biophys. Res. Commun. |volume=310 |issue= 3 |pages= 779–84 |year= 2003 |pmid= 14550271 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Scarpulla RC |title=Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells. |journal=Gene |volume=286 |issue= 1 |pages= 81–9 |year= 2002 |pmid= 11943463 |doi=
*cite journal | author=Andersson U, Scarpulla RC |title=Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells. |journal=Mol. Cell. Biol. |volume=21 |issue= 11 |pages= 3738–49 |year= 2001 |pmid= 11340167 |doi= 10.1128/MCB.21.11.3738-3749.2001
*cite journal | author=Nagase T, Ishikawa K, Miyajima N, "et al." |title=Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 1 |pages= 31–9 |year= 1998 |pmid= 9628581 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=

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