CARD8

Caspase recruitment domain family, member 8, also known as CARD8, is a human gene.cite web | title = Entrez Gene: CARD8 caspase recruitment domain family, member 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22900| accessdate = ]

PBB_Summary
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summary_text = Caspase recruitment domain (CARD)-containing proteins, such as CARD8, are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB; see MIM 164011) in the context of apoptosis or inflammation, respectively (Bouchier-Hayes et al., 2001). [supplied by OMIM] cite web | title = Entrez Gene: CARD8 caspase recruitment domain family, member 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22900| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Fontalba A, Martinez-Taboada V, Gutierrez O, "et al." |title=Deficiency of the NF-kappaB inhibitor caspase activating and recruitment domain 8 in patients with rheumatoid arthritis is associated with disease severity. |journal=J. Immunol. |volume=179 |issue= 7 |pages= 4867–73 |year= 2007 |pmid= 17878386 |doi=
*cite journal | author=Franke A, Rosenstiel P, Balschun T, "et al." |title=No association between the TUCAN (CARD8) Cys10Stop mutation and inflammatory bowel disease in a large retrospective German and a clinically well-characterized Norwegian sample. |journal=Gastroenterology |volume=132 |issue= 5 |pages= 2080–1 |year= 2007 |pmid= 17484912 |doi= 10.1053/j.gastro.2007.03.087
*cite journal | author=McGovern DP, Butler H, Ahmad T, "et al." |title=TUCAN (CARD8) genetic variants and inflammatory bowel disease. |journal=Gastroenterology |volume=131 |issue= 4 |pages= 1190–6 |year= 2006 |pmid= 17030188 |doi= 10.1053/j.gastro.2006.08.008
*cite journal | author=Checinska A, Giaccone G, Hoogeland BS, "et al." |title=TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells. |journal=BMC Cancer |volume=6 |issue= |pages= 166 |year= 2006 |pmid= 16796750 |doi= 10.1186/1471-2407-6-166
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Agostini L, Martinon F, Burns K, "et al." |title=NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. |journal=Immunity |volume=20 |issue= 3 |pages= 319–25 |year= 2004 |pmid= 15030775 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Stilo R, Leonardi A, Formisano L, "et al." |title=TUCAN/CARDINAL and DRAL participate in a common pathway for modulation of NF-kappaB activation. |journal=FEBS Lett. |volume=521 |issue= 1-3 |pages= 165–9 |year= 2002 |pmid= 12067710 |doi=
*cite journal | author=Zhang H, Fu W |title=NDPP1 is a novel CARD domain containing protein which can inhibit apoptosis and suppress NF-kappaB activation. |journal=Int. J. Oncol. |volume=20 |issue= 5 |pages= 1035–40 |year= 2002 |pmid= 11956601 |doi=
*cite journal | author=Razmara M, Srinivasula SM, Wang L, "et al." |title=CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis. |journal=J. Biol. Chem. |volume=277 |issue= 16 |pages= 13952–8 |year= 2002 |pmid= 11821383 |doi= 10.1074/jbc.M107811200
*cite journal | author=Bouchier-Hayes L, Conroy H, Egan H, "et al." |title=CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways. |journal=J. Biol. Chem. |volume=276 |issue= 47 |pages= 44069–77 |year= 2001 |pmid= 11551959 |doi= 10.1074/jbc.M107373200
*cite journal | author=Pathan N, Marusawa H, Krajewska M, "et al." |title=TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer. |journal=J. Biol. Chem. |volume=276 |issue= 34 |pages= 32220–9 |year= 2001 |pmid= 11408476 |doi= 10.1074/jbc.M100433200
*cite journal | author=Nagase T, Ishikawa K, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 1 |pages= 63–70 |year= 1999 |pmid= 10231032 |doi=

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