KLC3

KLC3

Kinesin light chain 3, also known as KLC3, is a human gene.cite web | title = Entrez Gene: KLC3 kinesin light chain 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=147700| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.cite web | title = Entrez Gene: KLC3 kinesin light chain 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=147700| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Zhang Y, Oko R, van der Hoorn FA |title=Rat kinesin light chain 3 associates with spermatid mitochondria. |journal=Dev. Biol. |volume=275 |issue= 1 |pages= 23–33 |year= 2004 |pmid= 15464570 |doi= 10.1016/j.ydbio.2004.07.014
*cite journal | author=Jin J, Smith FD, Stark C, "et al." |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Bhullar B, Zhang Y, Junco A, "et al." |title=Association of kinesin light chain with outer dense fibers in a microtubule-independent fashion. |journal=J. Biol. Chem. |volume=278 |issue= 18 |pages= 16159–68 |year= 2003 |pmid= 12594206 |doi= 10.1074/jbc.M213126200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Yang J, Liu X, Yue G, "et al." |title=Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet. |journal=J. Cell Biol. |volume=159 |issue= 3 |pages= 431–40 |year= 2002 |pmid= 12427867 |doi= 10.1083/jcb.200207153
*cite journal | author=Ichimura T, Wakamiya-Tsuruta A, Itagaki C, "et al." |title=Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein. |journal=Biochemistry |volume=41 |issue= 17 |pages= 5566–72 |year= 2002 |pmid= 11969417 |doi=
*cite journal | author=Junco A, Bhullar B, Tarnasky HA, van der Hoorn FA |title=Kinesin light-chain KLC3 expression in testis is restricted to spermatids. |journal=Biol. Reprod. |volume=64 |issue= 5 |pages= 1320–30 |year= 2001 |pmid= 11319135 |doi=
*cite journal | author=Rahman A, Kamal A, Roberts EA, Goldstein LS |title=Defective kinesin heavy chain behavior in mouse kinesin light chain mutants. |journal=J. Cell Biol. |volume=146 |issue= 6 |pages= 1277–88 |year= 1999 |pmid= 10491391 |doi=
*cite journal | author=Rahman A, Friedman DS, Goldstein LS |title=Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins. |journal=J. Biol. Chem. |volume=273 |issue= 25 |pages= 15395–403 |year= 1998 |pmid= 9624122 |doi=
*cite journal | author=Lamerdin JE, Stilwagen SA, Ramirez MH, "et al." |title=Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes. |journal=Genomics |volume=34 |issue= 3 |pages= 399–409 |year= 1996 |pmid= 8786141 |doi= 10.1006/geno.1996.0303

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