UCN3

UCN3

Urocortin 3 (stresscopin), also known as UCN3, is a human gene.cite web | title = Entrez Gene: UCN3 urocortin 3 (stresscopin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=114131| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.cite web | title = Entrez Gene: UCN3 urocortin 3 (stresscopin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=114131| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hauger RL, Grigoriadis DE, Dallman MF, "et al." |title=International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands. |journal=Pharmacol. Rev. |volume=55 |issue= 1 |pages= 21–6 |year= 2003 |pmid= 12615952 |doi= 10.1124/pr.55.1.3
*cite journal | author=Florio P, Torres PB, Torricelli M, "et al." |title=Human endometrium expresses urocortin II and III messenger RNA and peptides. |journal=Fertil. Steril. |volume=86 |issue= 6 |pages= 1766–70 |year= 2006 |pmid= 17074339 |doi= 10.1016/j.fertnstert.2006.05.041
*cite journal | author=Imperatore A, Florio P, Torres PB, "et al." |title=Urocortin 2 and urocortin 3 are expressed by the human placenta, deciduas, and fetal membranes. |journal=Am. J. Obstet. Gynecol. |volume=195 |issue= 1 |pages= 288–95 |year= 2006 |pmid= 16626608 |doi= 10.1016/j.ajog.2005.12.048
*cite journal | author=Saruta M, Takahashi K, Suzuki T, "et al." |title=Urocortin 3/stresscopin in human colon: possible modulators of gastrointestinal function during stressful conditions. |journal=Peptides |volume=26 |issue= 7 |pages= 1196–206 |year= 2005 |pmid= 15949638 |doi= 10.1016/j.peptides.2005.01.014
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Chang CL, Hsu SY |title=Ancient evolution of stress-regulating peptides in vertebrates. |journal=Peptides |volume=25 |issue= 10 |pages= 1681–8 |year= 2005 |pmid= 15476935 |doi= 10.1016/j.peptides.2004.05.022
*cite journal | author=Takahashi K, Totsune K, Murakami O, "et al." |title=Expression of urocortin III/stresscopin in human heart and kidney. |journal=J. Clin. Endocrinol. Metab. |volume=89 |issue= 4 |pages= 1897–903 |year= 2004 |pmid= 15070962 |doi=
*cite journal | author=Seres J, Bornstein SR, Seres P, "et al." |title=Corticotropin-releasing hormone system in human adipose tissue. |journal=J. Clin. Endocrinol. Metab. |volume=89 |issue= 2 |pages= 965–70 |year= 2004 |pmid= 14764822 |doi=
*cite journal | author=Chanalaris A, Lawrence KM, Stephanou A, "et al." |title=Protective effects of the urocortin homologues stresscopin (SCP) and stresscopin-related peptide (SRP) against hypoxia/reoxygenation injury in rat neonatal cardiomyocytes. |journal=J. Mol. Cell. Cardiol. |volume=35 |issue= 10 |pages= 1295–305 |year= 2004 |pmid= 14519439 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Lewis K, Li C, Perrin MH, "et al." |title=Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 13 |pages= 7570–5 |year= 2001 |pmid= 11416224 |doi= 10.1073/pnas.121165198
*cite journal | author=Hsu SY, Hsueh AJ |title=Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor. |journal=Nat. Med. |volume=7 |issue= 5 |pages= 605–11 |year= 2001 |pmid= 11329063 |doi= 10.1038/87936

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  • Urocortin — heißen mehrere aus etwa 40 Aminosäuren bestehenden Peptide, die in Säugetieren produziert werden. Sie besitzen 45 % Sequenzhomologie zum Corticotropin Releasing Factor (CRF). Im Mensch sind drei Urocortine bekannt, die an die CRF Rezeptoren… …   Deutsch Wikipedia

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