SOCS5

Suppressor of cytokine signaling 5, also known as SOCS5, is a human gene.cite web | title = Entrez Gene: SOCS5 suppressor of cytokine signaling 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9655| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.cite web | title = Entrez Gene: SOCS5 suppressor of cytokine signaling 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9655| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kile BT, Schulman BA, Alexander WS, "et al." |title=The SOCS box: a tale of destruction and degradation. |journal=Trends Biochem. Sci. |volume=27 |issue= 5 |pages= 235–41 |year= 2002 |pmid= 12076535 |doi=
*cite journal | author=Wang J, Campbell IL |title=Cytokine signaling in the brain: putting a SOCS in it? |journal=J. Neurosci. Res. |volume=67 |issue= 4 |pages= 423–7 |year= 2002 |pmid= 11835308 |doi=
*cite journal | author=Krebs DL, Hilton DJ |title=SOCS proteins: negative regulators of cytokine signaling. |journal=Stem Cells |volume=19 |issue= 5 |pages= 378–87 |year= 2001 |pmid= 11553846 |doi=
*cite journal | author=Ozaki A, Seki Y, Fukushima A, Kubo M |title=The control of allergic conjunctivitis by suppressor of cytokine signaling (SOCS)3 and SOCS5 in a murine model. |journal=J. Immunol. |volume=175 |issue= 8 |pages= 5489–97 |year= 2005 |pmid= 16210657 |doi=
*cite journal | author=Kario E, Marmor MD, Adamsky K, "et al." |title=Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling. |journal=J. Biol. Chem. |volume=280 |issue= 8 |pages= 7038–48 |year= 2005 |pmid= 15590694 |doi= 10.1074/jbc.M408575200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Bayle J, Letard S, Frank R, "et al." |title=Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling. |journal=J. Biol. Chem. |volume=279 |issue= 13 |pages= 12249–59 |year= 2004 |pmid= 14707129 |doi= 10.1074/jbc.M313381200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Seki Y, Hayashi K, Matsumoto A, "et al." |title=Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 20 |pages= 13003–8 |year= 2002 |pmid= 12242343 |doi= 10.1073/pnas.202477099
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Magrangeas F, Apiou F, Denis S, "et al." |title=Cloning and expression of CIS6, chromosome assignment to 3p22 and 2p21 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=88 |issue= 1-2 |pages= 78–81 |year= 2000 |pmid= 10773671 |doi=
*cite journal | author=Ishikawa K, Nagase T, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 3 |pages= 169–76 |year= 1998 |pmid= 9734811 |doi=
*cite journal | author=Hilton DJ, Richardson RT, Alexander WS, "et al." |title=Twenty proteins containing a C-terminal SOCS box form five structural classes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 1 |pages= 114–9 |year= 1998 |pmid= 9419338 |doi=

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