- MARCO
Macrophage receptor with collagenous structure, also known as MARCO, is a human
gene .cite web | title = Entrez Gene: MARCO macrophage receptor with collagenous structure| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8685| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.cite web | title = Entrez Gene: MARCO macrophage receptor with collagenous structure| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8685| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Elomaa O, Kangas M, Sahlberg C, "et al." |title=Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. |journal=Cell |volume=80 |issue= 4 |pages= 603–9 |year= 1995 |pmid= 7867067 |doi=
*cite journal | author=Elomaa O, Sankala M, Pikkarainen T, "et al." |title=Structure of the human macrophage MARCO receptor and characterization of its bacteria-binding region. |journal=J. Biol. Chem. |volume=273 |issue= 8 |pages= 4530–8 |year= 1998 |pmid= 9468508 |doi=
*cite journal | author=Kangas M, Brännström A, Elomaa O, "et al." |title=Structure and chromosomal localization of the human and murine genes for the macrophage MARCO receptor. |journal=Genomics |volume=58 |issue= 1 |pages= 82–9 |year= 1999 |pmid= 10331948 |doi= 10.1006/geno.1999.5811
*cite journal | author=Elshourbagy NA, Li X, Terrett J, "et al." |title=Molecular characterization of a human scavenger receptor, human MARCO. |journal=Eur. J. Biochem. |volume=267 |issue= 3 |pages= 919–26 |year= 2000 |pmid= 10651831 |doi=
*cite journal | author=Seta N, Granfors K, Sahly H, "et al." |title=Expression of host defense scavenger receptors in spondylarthropathy. |journal=Arthritis Rheum. |volume=44 |issue= 4 |pages= 931–9 |year= 2001 |pmid= 11315932 |doi= 10.1002/1529-0131(200104)44:4<931::AID-ANR150>3.0.CO;2-T |doilabel=10.1002/1529-0131(200104)44:4931::AID-ANR1503.0.CO;2-T
*cite journal | author=Brännström A, Sankala M, Tryggvason K, Pikkarainen T |title=Arginine residues in domain V have a central role for bacteria-binding activity of macrophage scavenger receptor MARCO. |journal=Biochem. Biophys. Res. Commun. |volume=290 |issue= 5 |pages= 1462–9 |year= 2002 |pmid= 11820786 |doi= 10.1006/bbrc.2002.6378
*cite journal | author=Sankala M, Brännström A, Schulthess T, "et al." |title=Characterization of recombinant soluble macrophage scavenger receptor MARCO. |journal=J. Biol. Chem. |volume=277 |issue= 36 |pages= 33378–85 |year= 2002 |pmid= 12097327 |doi= 10.1074/jbc.M204494200
*cite journal | author=Mirani M, Elenkov I, Volpi S, "et al." |title=HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection. |journal=J. Immunol. |volume=169 |issue= 11 |pages= 6361–8 |year= 2002 |pmid= 12444143 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bin LH, Nielson LD, Liu X, "et al." |title=Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair. |journal=J. Immunol. |volume=171 |issue= 2 |pages= 924–30 |year= 2003 |pmid= 12847263 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Arredouani MS, Palecanda A, Koziel H, "et al." |title=MARCO is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages. |journal=J. Immunol. |volume=175 |issue= 9 |pages= 6058–64 |year= 2005 |pmid= 16237101 |doi=
*cite journal | author=Liu T, Qian WJ, Gritsenko MA, "et al." |title=Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. |journal=J. Proteome Res. |volume=4 |issue= 6 |pages= 2070–80 |year= 2006 |pmid= 16335952 |doi= 10.1021/pr0502065PBB_Controls
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