RBBP6

Retinoblastoma binding protein 6, also known as RBBP6, is a human gene.cite web | title = Entrez Gene: RBBP6 retinoblastoma binding protein 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5930| accessdate = ]

PBB_Summary
section_title =
summary_text = The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.cite web | title = Entrez Gene: RBBP6 retinoblastoma binding protein 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5930| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Sakai Y, Saijo M, Coelho K, "et al." |title=cDNA sequence and chromosomal localization of a novel human protein, RBQ-1 (RBBP6), that binds to the retinoblastoma gene product. |journal=Genomics |volume=30 |issue= 1 |pages= 98–101 |year= 1996 |pmid= 8595913 |doi= 10.1006/geno.1995.0017
*cite journal | author=Simons A, Melamed-Bessudo C, Wolkowicz R, "et al." |title=PACT: cloning and characterization of a cellular p53 binding protein that interacts with Rb. |journal=Oncogene |volume=14 |issue= 2 |pages= 145–55 |year= 1997 |pmid= 9010216 |doi= 10.1038/sj.onc.1200825
*cite journal | author=Gao S, Witte MM, Scott RE |title=P2P-R protein localizes to the nucleolus of interphase cells and the periphery of chromosomes in mitotic cells which show maximum P2P-R immunoreactivity. |journal=J. Cell. Physiol. |volume=191 |issue= 2 |pages= 145–54 |year= 2002 |pmid= 12064457 |doi= 10.1002/jcp.10084
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Yoshitake Y, Nakatsura T, Monji M, "et al." |title=Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis. |journal=Clin. Cancer Res. |volume=10 |issue= 19 |pages= 6437–48 |year= 2005 |pmid= 15475430 |doi= 10.1158/1078-0432.CCR-04-0841
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Scott RE, White-Grindley E, Ruley HE, "et al." |title=P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA. |journal=J. Cell. Physiol. |volume=204 |issue= 1 |pages= 99–105 |year= 2005 |pmid= 15617101 |doi= 10.1002/jcp.20263
*cite journal | author=Pugh DJ, Ab E, Faro A, "et al." |title=DWNN, a novel ubiquitin-like domain, implicates RBBP6 in mRNA processing and ubiquitin-like pathways. |journal=BMC Struct. Biol. |volume=6 |issue= |pages= 1 |year= 2006 |pmid= 16396680 |doi= 10.1186/1472-6807-6-1
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

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