SETD2

SET domain containing 2, also known as SETD2, is a human gene.cite web | title = Entrez Gene: SETD2 SET domain containing 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29072| accessdate = ]

PBB_Summary
section_title =
summary_text = Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.cite web | title = Entrez Gene: SETD2 SET domain containing 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29072| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Faber PW, Barnes GT, Srinidhi J, "et al." |title=Huntingtin interacts with a family of WW domain proteins. |journal=Hum. Mol. Genet. |volume=7 |issue= 9 |pages= 1463–74 |year= 1998 |pmid= 9700202 |doi=
*cite journal | author=Passani LA, Bedford MT, Faber PW, "et al." |title=Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis. |journal=Hum. Mol. Genet. |volume=9 |issue= 14 |pages= 2175–82 |year= 2000 |pmid= 10958656 |doi=
*cite journal | author=Zhang QH, Ye M, Wu XY, "et al." |title=Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. |journal=Genome Res. |volume=10 |issue= 10 |pages= 1546–60 |year= 2001 |pmid= 11042152 |doi=
*cite journal | author=Nagase T, Kikuno R, Hattori A, "et al." |title=Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 6 |pages= 347–55 |year= 2001 |pmid= 11214970 |doi=
*cite journal | author=Rega S, Stiewe T, Chang DI, "et al." |title=Identification of the full-length huntingtin- interacting protein p231HBP/HYPB as a DNA-binding factor. |journal=Mol. Cell. Neurosci. |volume=18 |issue= 1 |pages= 68–79 |year= 2001 |pmid= 11461154 |doi= 10.1006/mcne.2001.1004
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Sun XJ, Wei J, Wu XY, "et al." |title=Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase. |journal=J. Biol. Chem. |volume=280 |issue= 42 |pages= 35261–71 |year= 2005 |pmid= 16118227 |doi= 10.1074/jbc.M504012200
*cite journal | author=Li M, Phatnani HP, Guan Z, "et al." |title=Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 49 |pages= 17636–41 |year= 2006 |pmid= 16314571 |doi= 10.1073/pnas.0506350102
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

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