PPP1R14A

Protein phosphatase 1, regulatory (inhibitor) subunit 14A, also known as PPP1R14A, is a human gene.cite web | title = Entrez Gene: PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=94274| accessdate = ]

PBB_Summary
section_title =
summary_text = PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase (see MIM 603768). Inhibition leads to increased myosin phosphorylation and enhances smooth muscle contraction in the absence of increased intracellular Ca(2+) concentration. [supplied by OMIM] cite web | title = Entrez Gene: PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=94274| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Eto M, Ohmori T, Suzuki M, "et al." |title=A novel protein phosphatase-1 inhibitory protein potentiated by protein kinase C. Isolation from porcine aorta media and characterization. |journal=J. Biochem. |volume=118 |issue= 6 |pages= 1104–7 |year= 1996 |pmid= 8720121 |doi=
*cite journal | author=Eto M, Senba S, Morita F, Yazawa M |title=Molecular cloning of a novel phosphorylation-dependent inhibitory protein of protein phosphatase-1 (CPI17) in smooth muscle: its specific localization in smooth muscle. |journal=FEBS Lett. |volume=410 |issue= 2-3 |pages= 356–60 |year= 1997 |pmid= 9237662 |doi=
*cite journal | author=Koyama M, Ito M, Feng J, "et al." |title=Phosphorylation of CPI-17, an inhibitory phosphoprotein of smooth muscle myosin phosphatase, by Rho-kinase. |journal=FEBS Lett. |volume=475 |issue= 3 |pages= 197–200 |year= 2000 |pmid= 10869555 |doi=
*cite journal | author=Hamaguchi T, Ito M, Feng J, "et al." |title=Phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by protein kinase N. |journal=Biochem. Biophys. Res. Commun. |volume=274 |issue= 3 |pages= 825–30 |year= 2000 |pmid= 10924361 |doi= 10.1006/bbrc.2000.3225
*cite journal | author=Yamawaki K, Ito M, Machida H, "et al." |title=Identification of human CPI-17, an inhibitory phosphoprotein for myosin phosphatase. |journal=Biochem. Biophys. Res. Commun. |volume=285 |issue= 4 |pages= 1040–5 |year= 2001 |pmid= 11467857 |doi= 10.1006/bbrc.2001.5290
*cite journal | author=Li Z, Yu L, Zhang Y, "et al." |title=Identification of human, mouse and rat PPP1R14A, protein phosphatase-1 inhibitor subunit 14A, & mapping human PPP1R14A to chromosome 19q13.13-q13.2. |journal=Mol. Biol. Rep. |volume=28 |issue= 2 |pages= 91–101 |year= 2002 |pmid= 11931393 |doi=
*cite journal | author=Dubois T, Howell S, Zemlickova E, Aitken A |title=Identification of casein kinase Ialpha interacting protein partners. |journal=FEBS Lett. |volume=517 |issue= 1-3 |pages= 167–71 |year= 2002 |pmid= 12062430 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Liu QR, Zhang PW, Lin Z, "et al." |title=GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA. |journal=Biochem. J. |volume=377 |issue= Pt 1 |pages= 171–81 |year= 2004 |pmid= 12974676 |doi= 10.1042/BJ20030128
*cite journal | author=Zemlickova E, Johannes FJ, Aitken A, Dubois T |title=Association of CPI-17 with protein kinase C and casein kinase I. |journal=Biochem. Biophys. Res. Commun. |volume=316 |issue= 1 |pages= 39–47 |year= 2004 |pmid= 15003508 |doi= 10.1016/j.bbrc.2004.02.014
*cite journal | author=Kolosova IA, Ma SF, Adyshev DM, "et al." |title=Role of CPI-17 in the regulation of endothelial cytoskeleton. |journal=Am. J. Physiol. Lung Cell Mol. Physiol. |volume=287 |issue= 5 |pages= L970–80 |year= 2004 |pmid= 15234908 |doi= 10.1152/ajplung.00398.2003
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Jin H, Sperka T, Herrlich P, Morrison H |title=Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase. |journal=Nature |volume=442 |issue= 7102 |pages= 576–9 |year= 2006 |pmid= 16885985 |doi= 10.1038/nature04856
*cite journal | author=Morin C, Sirois M, Echave V, "et al." |title=Epoxyeicosatrienoic acid relaxing effects involve Ca2+-activated K+ channel activation and CPI-17 dephosphorylation in human bronchi. |journal=Am. J. Respir. Cell Mol. Biol. |volume=36 |issue= 5 |pages= 633–41 |year= 2007 |pmid= 17237191 |doi= 10.1165/rcmb.2006-0281OC
*cite journal | author=Lartey J, Smith M, Pawade J, "et al." |title=Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor. |journal=Biol. Reprod. |volume=76 |issue= 6 |pages= 971–82 |year= 2007 |pmid= 17301291 |doi= 10.1095/biolreprod.106.058982

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