RSU1

RSU1

Ras suppressor protein 1, also known as RSU1, is a human gene.cite web | title = Entrez Gene: RSU1 Ras suppressor protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6251| accessdate = ]

PBB_Summary
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summary_text = This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors.cite web | title = Entrez Gene: RSU1 Ras suppressor protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6251| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Cutler ML, Bassin RH, Zanoni L, Talbot N |title=Isolation of rsp-1, a novel cDNA capable of suppressing v-Ras transformation. |journal=Mol. Cell. Biol. |volume=12 |issue= 9 |pages= 3750–6 |year= 1992 |pmid= 1508180 |doi=
*cite journal | author=Tsuda T, Marinetti MR, Masuelli L, Cutler ML |title=The Ras suppressor RSU-1 localizes to 10p13 and its expression in the U251 glioblastoma cell line correlates with a decrease in growth rate and tumorigenic potential. |journal=Oncogene |volume=11 |issue= 2 |pages= 397–403 |year= 1995 |pmid= 7624154 |doi=
*cite journal | author=Matoba R, Okubo K, Hori N, "et al." |title=The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression. |journal=Gene |volume=146 |issue= 2 |pages= 199–207 |year= 1994 |pmid= 8076819 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Tsuda T, Cutler ML |title=Human RSU1 is highly homologous to mouse Rsu-1 and localizes to human chromosome 10. |journal=Genomics |volume=18 |issue= 2 |pages= 461–2 |year= 1994 |pmid= 8288261 |doi= 10.1006/geno.1993.1503
*cite journal | author=Masuelli L, Cutler ML |title=Increased expression of the Ras suppressor Rsu-1 enhances Erk-2 activation and inhibits Jun kinase activation. |journal=Mol. Cell. Biol. |volume=16 |issue= 10 |pages= 5466–76 |year= 1996 |pmid= 8816460 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Chunduru S, Kawami H, Gullick R, "et al." |title=Identification of an alternatively spliced RNA for the Ras suppressor RSU-1 in human gliomas. |journal=J. Neurooncol. |volume=60 |issue= 3 |pages= 201–11 |year= 2003 |pmid= 12510772 |doi=
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Aboulaich N, Vainonen JP, Strålfors P, Vener AV |title=Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes. |journal=Biochem. J. |volume=383 |issue= Pt 2 |pages= 237–48 |year= 2005 |pmid= 15242332 |doi= 10.1042/BJ20040647
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Dougherty GW, Chopp T, Qi SM, Cutler ML |title=The Ras suppressor Rsu-1 binds to the LIM 5 domain of the adaptor protein PINCH1 and participates in adhesion-related functions. |journal=Exp. Cell Res. |volume=306 |issue= 1 |pages= 168–79 |year= 2005 |pmid= 15878342 |doi= 10.1016/j.yexcr.2005.01.025
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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