- RPL35A
Ribosomal protein L35a, also known as RPL35A, is a human
gene .cite web | title = Entrez Gene: RPL35A ribosomal protein L35a| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6165| accessdate = ]PBB_Summary
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summary_text = Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L35AE family of ribosomal proteins. It is located in the cytoplasm. The rat protein has been shown to bind to both initiator and elongator tRNAs, and thus, it is located at the P site, or P and A sites, of the ribosome. Although this gene was originally mapped to chromosome 18, it has been established that it is located at 3q29-qter. Transcript variants utilizing alternative transcription initiation sites and alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.cite web | title = Entrez Gene: RPL35A ribosomal protein L35a| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6165| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Wool IG, Chan YL, Glück A |title=Structure and evolution of mammalian ribosomal proteins. |journal=Biochem. Cell Biol. |volume=73 |issue= 11-12 |pages= 933–47 |year= 1996 |pmid= 8722009 |doi=
*cite journal | author=Feo S, Davies B, Fried M |title=The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome. |journal=Genomics |volume=13 |issue= 1 |pages= 201–7 |year= 1992 |pmid= 1577483 |doi=
*cite journal | author=Herzog H, Höfferer L, Schneider R, Schweiger M |title=cDNA encoding the human homologue of rat ribosomal protein L35a. |journal=Nucleic Acids Res. |volume=18 |issue= 15 |pages= 4600 |year= 1990 |pmid= 2388839 |doi=
*cite journal | author=Kato S, Sekine S, Oh SW, "et al." |title=Construction of a human full-length cDNA bank. |journal=Gene |volume=150 |issue= 2 |pages= 243–50 |year= 1995 |pmid= 7821789 |doi=
*cite journal | author=Colombo P, Read M, Fried M |title=The human L35a ribosomal protein (RPL35A) gene is located at chromosome band 3q29-qter. |journal=Genomics |volume=32 |issue= 1 |pages= 148–50 |year= 1996 |pmid= 8786106 |doi= 10.1006/geno.1996.0093
*cite journal | author=Kenmochi N, Kawaguchi T, Rozen S, "et al." |title=A map of 75 human ribosomal protein genes. |journal=Genome Res. |volume=8 |issue= 5 |pages= 509–23 |year= 1998 |pmid= 9582194 |doi=
*cite journal | author=Kroes RA, Jastrow A, McLone MG, "et al." |title=The identification of novel therapeutic targets for the treatment of malignant brain tumors. |journal=Cancer Lett. |volume=156 |issue= 2 |pages= 191–8 |year= 2000 |pmid= 10880769 |doi=
*cite journal | author=Yoshihama M, Uechi T, Asakawa S, "et al." |title=The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. |journal=Genome Res. |volume=12 |issue= 3 |pages= 379–90 |year= 2002 |pmid= 11875025 |doi= 10.1101/gr.214202
*cite journal | author=Lopez CD, Martinovsky G, Naumovski L |title=Inhibition of cell death by ribosomal protein L35a. |journal=Cancer Lett. |volume=180 |issue= 2 |pages= 195–202 |year= 2002 |pmid= 12175552 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kasai H, Nadano D, Hidaka E, "et al." |title=Differential expression of ribosomal proteins in human normal and neoplastic colorectum. |journal=J. Histochem. Cytochem. |volume=51 |issue= 5 |pages= 567–74 |year= 2003 |pmid= 12704204 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134PBB_Controls
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