SEC31A

SEC31 homolog A (S. cerevisiae), also known as SEC31A, is a human gene.cite web | title = Entrez Gene: SEC31A SEC31 homolog A (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22872| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms.cite web | title = Entrez Gene: SEC31A SEC31 homolog A (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22872| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Nagase T, Ishikawa K, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 6 |pages= 355–64 |year= 1999 |pmid= 10048485 |doi=
*cite journal | author=Tang BL, Zhang T, Low DY, "et al." |title=Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport. |journal=J. Biol. Chem. |volume=275 |issue= 18 |pages= 13597–604 |year= 2000 |pmid= 10788476 |doi=
*cite journal | author=Kim JH, Hong JA, Pih KT, Hwang I |title=Identification and isolation of differentially expressed genes in osmotically stressed human oral keratinocytes. |journal=Arch. Oral Biol. |volume=46 |issue= 4 |pages= 335–41 |year= 2001 |pmid= 11269867 |doi=
*cite journal | author=Wistow G, Bernstein SL, Wyatt MK, "et al." |title=Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. |journal=Mol. Vis. |volume=8 |issue= |pages= 205–20 |year= 2002 |pmid= 12107410 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Loïodice I, Alves A, Rabut G, "et al." |title=The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis. |journal=Mol. Biol. Cell |volume=15 |issue= 7 |pages= 3333–44 |year= 2005 |pmid= 15146057 |doi= 10.1091/mbc.E03-12-0878
*cite journal | author=Panagopoulos I, Nilsson T, Domanski HA, "et al." |title=Fusion of the SEC31L1 and ALK genes in an inflammatory myofibroblastic tumor. |journal=Int. J. Cancer |volume=118 |issue= 5 |pages= 1181–6 |year= 2006 |pmid= 16161041 |doi= 10.1002/ijc.21490
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Stagg SM, Gürkan C, Fowler DM, "et al." |title=Structure of the Sec13/31 COPII coat cage. |journal=Nature |volume=439 |issue= 7073 |pages= 234–8 |year= 2006 |pmid= 16407955 |doi= 10.1038/nature04339
*cite journal | author=Yamasaki A, Tani K, Yamamoto A, "et al." |title=The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A. |journal=Mol. Biol. Cell |volume=17 |issue= 11 |pages= 4876–87 |year= 2007 |pmid= 16957052 |doi= 10.1091/mbc.E06-05-0444
*cite journal | author=Shibata H, Suzuki H, Yoshida H, Maki M |title=ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner. |journal=Biochem. Biophys. Res. Commun. |volume=353 |issue= 3 |pages= 756–63 |year= 2007 |pmid= 17196169 |doi= 10.1016/j.bbrc.2006.12.101
*cite journal | author=la Cour JM, Mollerup J, Berchtold MW |title=ALG-2 oscillates in subcellular localization, unitemporally with calcium oscillations. |journal=Biochem. Biophys. Res. Commun. |volume=353 |issue= 4 |pages= 1063–7 |year= 2007 |pmid= 17214967 |doi= 10.1016/j.bbrc.2006.12.143

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