HNRNPR

Heterogeneous nuclear ribonucleoprotein R, also known as HNRPR, is a human gene.cite web | title = Entrez Gene: HNRPR heterogeneous nuclear ribonucleoprotein R| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10236| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif.cite web | title = Entrez Gene: HNRPR heterogeneous nuclear ribonucleoprotein R| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10236| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hassfeld W, Chan EK, Mathison DA, "et al." |title=Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP P. |journal=Nucleic Acids Res. |volume=26 |issue= 2 |pages= 439–45 |year= 1998 |pmid= 9421497 |doi=
*cite journal | author=Mourelatos Z, Abel L, Yong J, "et al." |title=SMN interacts with a novel family of hnRNP and spliceosomal proteins. |journal=EMBO J. |volume=20 |issue= 19 |pages= 5443–52 |year= 2001 |pmid= 11574476 |doi= 10.1093/emboj/20.19.5443
*cite journal | author=Rossoll W, Kröning AK, Ohndorf UM, "et al." |title=Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? |journal=Hum. Mol. Genet. |volume=11 |issue= 1 |pages= 93–105 |year= 2002 |pmid= 11773003 |doi=
*cite journal | author=Jurica MS, Licklider LJ, Gygi SR, "et al." |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=
*cite journal | author=Wada K, Inoue K, Hagiwara M |title=Identification of methylated proteins by protein arginine N-methyltransferase 1, PRMT1, with a new expression cloning strategy. |journal=Biochim. Biophys. Acta |volume=1591 |issue= 1-3 |pages= 1–10 |year= 2002 |pmid= 12183049 |doi=
*cite journal | author=Angenstein F, Evans AM, Settlage RE, "et al." |title=A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. |journal=J. Neurosci. |volume=22 |issue= 20 |pages= 8827–37 |year= 2002 |pmid= 12388589 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Hassel S, Eichner A, Yakymovych M, "et al." |title=Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. |journal=Proteomics |volume=4 |issue= 5 |pages= 1346–58 |year= 2004 |pmid= 15188402 |doi= 10.1002/pmic.200300770
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Huang J, Chen XH, Wu K, Xu P |title=Cloning and expression of a novel isoform of heterogeneous nuclear ribonucleoprotein-R. |journal=Neuroreport |volume=16 |issue= 7 |pages= 727–30 |year= 2005 |pmid= 15858414 |doi=
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Szafranski K, Schindler S, Taudien S, "et al." |title=Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. |journal= |volume=8 |issue= 8 |pages= R154 |year= |pmid= 17672918 |doi= 10.1186/gb-2007-8-8-r154

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