RASSF2

Ras association (RalGDS/AF-6) domain family 2, also known as RASSF2, is a human gene.cite web | title = Entrez Gene: RASSF2 Ras association (RalGDS/AF-6) domain family 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9770| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported.cite web | title = Entrez Gene: RASSF2 Ras association (RalGDS/AF-6) domain family 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9770| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Nagase T, Seki N, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=3 |issue= 1 |pages= 17–24 |year= 1996 |pmid= 8724849 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Comincini S, Castiglioni BM, Foti GM, "et al." |title=Isolation and molecular characterization of rasfadin, a novel gene in the vicinity of the bovine prion gene. |journal=Mamm. Genome |volume=12 |issue= 2 |pages= 150–6 |year= 2001 |pmid= 11210185 |doi=
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Vos MD, Ellis CA, Elam C, "et al." |title=RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor. |journal=J. Biol. Chem. |volume=278 |issue= 30 |pages= 28045–51 |year= 2003 |pmid= 12732644 |doi= 10.1074/jbc.M300554200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Fujita H, Fukuhara S, Sakurai A, "et al." |title=Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes. |journal=J. Biol. Chem. |volume=280 |issue= 6 |pages= 5022–31 |year= 2005 |pmid= 15569673 |doi= 10.1074/jbc.M409701200
*cite journal | author=Hesson LB, Wilson R, Morton D, "et al." |title=CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations. |journal=Oncogene |volume=24 |issue= 24 |pages= 3987–94 |year= 2005 |pmid= 15806169 |doi= 10.1038/sj.onc.1208566
*cite journal | author=Akino K, Toyota M, Suzuki H, "et al." |title=The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer. |journal=Gastroenterology |volume=129 |issue= 1 |pages= 156–69 |year= 2005 |pmid= 16012945 |doi=
*cite journal | author=Endoh M, Tamura G, Honda T, "et al." |title=RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer. |journal=Br. J. Cancer |volume=93 |issue= 12 |pages= 1395–9 |year= 2006 |pmid= 16265349 |doi= 10.1038/sj.bjc.6602854
*cite journal | author=Zhang Z, Sun D, Van do N, "et al." |title=Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma. |journal=Int. J. Cancer |volume=120 |issue= 1 |pages= 32–8 |year= 2007 |pmid= 17013896 |doi= 10.1002/ijc.22185
*cite journal | author=Park HW, Kang HC, Kim IJ, "et al." |title=Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers. |journal=Int. J. Cancer |volume=120 |issue= 1 |pages= 7–12 |year= 2007 |pmid= 17013898 |doi= 10.1002/ijc.22276
*cite journal | author=Kumari G, Singhal PK, Rao MR, Mahalingam S |title=Nuclear transport of Ras-associated tumor suppressor proteins: different transport receptor binding specificities for arginine-rich nuclear targeting signals. |journal=J. Mol. Biol. |volume=367 |issue= 5 |pages= 1294–311 |year= 2007 |pmid= 17320110 |doi= 10.1016/j.jmb.2007.01.026
*cite journal | author=Kaira K, Sunaga N, Tomizawa Y, "et al." |title=Epigenetic inactivation of the RAS-effector gene RASSF2 in lung cancers. |journal=Int. J. Oncol. |volume=31 |issue= 1 |pages= 169–73 |year= 2007 |pmid= 17549418 |doi=

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